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Transcript
Chapter 12 DNA and RNA
are analogous to the rungs of a twisted ladder,
while the sugar-phosphate backbones of the double
helix are analogous to the sides of a twisted ladder.
10. Approximately 28% of the bases would be
thymine.
and frameshift mutations are both point mutations,
because they occur at a single point in the DNA
sequence. However, a substitution affects only a single codon, whereas a frameshift mutation affects all
the codons that follow the point of the mutation.
9. Polyploid plants are often larger and stronger.
This benefits humans by increasing agricultural production and the food supply. 10. An insertion, or
frameshift mutation, has occurred.
Section Review 12-2
Section Review 12-5
1. separates 2. two; four 3. base pairing 4. original
strand 5. new strand 6. original strand 7. new
strand 8. By coiling and folding very tightly, the
DNA of a bacterium is able to fit inside of its cell.
9. Typically, chromosomal fibers are dispersed and
are not visible. During mitosis, however, they
become so tightly packed together as to be visible
under a light microscope.
1. The lac genes in E. coli are turned off by repressors. 2. The lac genes in E. coli are turned on by the
presence of lactose. 3. Most eukaryotic genes are
controlled individually. 4. Both prokaryotes and
Section Review 12-1
1. c 2. b 3. a 4. double helix 5. Watson, Crick
6. hydrogen bonds 7. nucleotide 8. sugar-phosphate backbone 9. The hydrogen bonds of DNA
Section Review 12-3
1. messenger RNA, transfer RNA, ribosomal RNA
2. transcription 3. polymerase 4. translation
5. anticodon 6. Both DNA and RNA consist of a
© Pearson Education, Inc. All rights reserved.
ANSWER KEY
long chain of nucleotides. DNA however, contains
the base thymine. RNA contains uracil in placce of
thymine. DNA is double-stranded; RNA is singlestranded. DNA has a deoxyribose sugar; RNA has a
ribose sugar. 7. Messenger RNA carries protein
assembly instructions, ribosomal RNA helps to
assemble proteins, and transfer RNA carries amino
acids used in the construction of proteins.
8. Answers may vary. Having a sequence of DNA
that could be edited into several different mRNA
molecules makes it possible for a single gene to produce several different proteins specifically used in
different tissues. This allows a cell to carry less genetic material. It also makes it possible for very small
changes in DNA sequences to have a large change in
gene expression. This is a mechanism for evolutionary change. 9. The sequence CGCUAUAGC would
produce the amino acid sequence arginine, tyrosine,
and serine. 10. During transcription, the DNA
would produce mRNA in which the third base is C,
not A. Translation however, would be unaffected
because the original and the altered codons, CGA
and CGC, both specify the amino acid arginine.
eukaryotes have sequences that repress and promote gene expression. However, eukaryotic genes
tend to be individually controlled and their regulatory sequences are much more complex.
5. Organisms that are more complex, such as
eukaryotes, have cells that are specialized for specific functions. Gene regulation needs to be more
complex to produce these specialized cells for complex organisms. 6. Even though they belong to different tissues, the different cells of an organism
possess the same DNA. However, cells express only
a small portion of the DNA they possess, with cells
in different tissues expressing different portions of
DNA. 7. The lac operon allows E. coli to use lactose
as a food. 8. The TATA box is a region of DNA that
helps position RNA polymerase by marking a point
just before the point at which transcription begins.
9. The hox genes seem to function almost identically in humans and fruit flies; they control the differentiation of cells and tissues in the growing
embryo. 10. Possible student answer: Because
these genes have changed very little in 600 million
years, it can be inferred that mutations, if not fatal,
are strongly selected against.
Chapter Vocabulary Review
1. transfer RNA 2. messenger RNA 3. ribosomal
RNA 4. a 5. d 6. c 7. b 8. k 9. e 10. g 11. i
12. f 13. l 14. h 15. j 16. nucleotide 17. base
pairing 18. chromatin 19. transcription 20. RNA
polymerase 21. exons 22. translation 23. anticodon 24. operator 25. hox genes
Section Review 12-4
Enrichment
1. mutations 2. gene mutations 3. chromosomal
mutation 4. deletion: involves the loss of all or part
of a chromosome 5. duplication: produces extra
copies of parts of a chromosome 6. inversion:
1. A radioisotope that was too strongly radioactive
might disrupt the normal functioning of the cell. A
radioisotope that was too weakly radioactive might
be difficult to measure. 2. Because the scientist
needs to look at the components of the cell to see if
they contain tracer molecules, a quantitative assay
might work best.
reverses the direction of parts of chromosomes
7. translocation: occurs when part of one chromosome
breaks off and attaches to another 8. Substitution
Teaching Resources /Chapter 12
157
Graphic Organizer
1. DNA molecule “unzips” and the two strands
unwind. 2. Unwound strands of DNA serve as templates for new DNA. 3. DNA polymerase joins individual nucleotides to produce a new strand. 4. DNA
polymerase proofreads the new strands.
Exploration
Analyze and Conclude 1. Yes, the new DNA
sequence should be identical to the original
sequence. 2. Each cell receives a DNA molecule
consisting of a new strand and an original strand.
3. Mutations would occur that might affect the functions of the proteins specified by the DNA sequence.
These mutations could affect the life of the cell.
4. Students may say that the procedure modeled
DNA replication fairly well because all the steps of
DNA replication could be shown, including the
structure of DNA, complementary nucleotides, and
the action of DNA polymerase in forming a new
strand of DNA. 5. Students’ models should accurately represent DNA replication.
© Pearson Education, Inc. All rights reserved.
158
Teaching Resources /Chapter 12