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  chemicals released by vesicles in sending neuron travel across the synapse and bind to receptor sites on receiving neuron 2 TYPES = EXCITATORY = stimulate the brain, increase the likelihood that the neuron will fire an action potential INHIBITORY = calm the brain, balance mood & are depleted when excitatory are overactive Neurotransmitters bind to the receptors of the receiving neuron in a “key-lock mechanism”.  Serotonin  various functions = body temp., sleep, mood, appetite, and pain  Low levels =implicated in depression & probs with immune syst.  High = Serotonin Syndrome  stimulant medications or caffeine in your daily regimen can cause a depletion of serotonin   Norepinephrine (AKA Noradreneline)  Prepares you for action  important for attentiveness, emotions, sleeping, dreaming, and learning  causes blood vessels to contract & heart rate to increase GABA  Gamma-Amino Butyric Acid  An inhibitory neurotransmitter  “nature’s VALIUM-like substance”  Related probs = anxiety, seizures, Huntington’s disease  Valium and similar antianxiety drugs work at GABA synapses   Dopamine  main focus neurotransmitter  Affects neurons associated with voluntary movement  role in learning, memory, and emotions  Loss of dopamine-producing cells = Parkinson’s Disease  Excess = focusing issues, less motivation, schizophrenia  Stimulants (ex: cocaine, meds for ADD/ADHD, caffeine) cause dopamine to be pushed into the synapse so that focus is improved  BUT cause a depletion over time Acetylcholine  triggers muscle contraction  important role in arousal and attention  Loss = linked to Alzheimer’s Disease  Endorphins  linked to pain control and to pleasure  Reduce pain by inhibiting or “turning down” neurons that transmit pain information  natural, opiate-like neurotransmitters “morphine within”    Dopamine pathways are involved with diseases such as Parkinson’s disease  caused by a deterioration of brain neuron’s that produce dopamine (it is still unknown why this occurs) Although not the sole cause of schizophrenia, dopamine unbalance is consistently seen found in patients with schizophrenia Drugs that prevent dopamine from binding to receptors reduce the symptoms of schizophrenia  Agonist   Increases production Activates the neuron receptor that it attaches to  Antagonist   Decreases production Deactivates the neuron receptor that it attaches to
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            