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Transcript
CARBOHYDRATES Monosaccharides • Found in the cytosol and in organelles • Use for energy production and in biosynthesis Simple polysaccharides • Glycogen and starch polymers of glucose • Glycogen in granules in cytoplasm in muscle and liver cells ribosome mitochondrion Rough endo. reticulum cell membrane cytoplasm cytosol lysosome nascent glycoproteins ER peroxisome free ribosome ER-attached ribosome GAGs smooth endoplasmic reticulum cell membrane glycoprotein cell membrane glycolipid free ribosome Golgi complex Secreted glycoproteins (not to scale) Glycoproteins Glycolipids • Found in cell membrane • Involved in signaling across the membrane • Recognition sites for ligands • Recognition sites for binding other biomolecules • Minimizes protein misfolding of protein part • Increases stability of protein Glycosoaminoglycans GAGs • Linear, unbranched polysaccharide with dissacharide repeat of a hexose and hexosamine monsacharide • Highly charge with carboxyl and sulfate groups • Properties (high viscosity, low compressibility) useful for joints Secreted proteoglycans • GAGS covalently attached to protein core • components of the extracellular matrix • Involved in cell signaling and cell binding