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Transcript
Where do mutations occur? Which mutations are significant for future generations? How are mutations connected to the theory of Evolution? Where do mutations occur? Read LE 4 (page 41-42) Traits & Fates; Do TASK #1-3 using the Pink Sheet with mRNA sequences of Normal Hemoglobin (A) Sickle Hemoglobin (S) Use the decoding / codon sheet or p.42 chart to determine the amin0 acid sequence Answer the analysis questions #1 -5 in notebook Share your answer with table partner Volunteer(s) to share your answers… Change in DNA involving A single nucleotide A few nucleotides (sequences) within a gene or chromosome Large sections of a chromosome Hemoglobin Molecule involves a single nucleotide change DNA Protein Trait Read page 43 and complete TASK in pairs Each pair will be assigned a group number[1- 7] Each pair uses a white board to show your error in the DNA sequence ALL start with TACCGTCTGAAAGGT Write this DNA sense strand code in notebook OR on back of pink sheet! Transcribe and then Translate to the resulting protein Use the Doc Camera to show your work Describe what your group did… How it altered the amino acid sequence… What implications this may have… Where do these changes occur? What is the difference between a change in a sex cell and a body cell mutation? Which is needed for the variations within a population for natural selection? During DNA Replication Environmental Causes: Radiation Chemicals Most mutations are random and occur in regions of DNA that do NOT code for proteins --- Called SILENT MUTATIONS Harmless Does not affect the production of a ____________ because it does not change its DNA sequence Harmful Changes the production of a ______________ which causes harm (illness or lethal) Helpful Changes the production of a _____________ which makes the organism more fitted to its environment Harmless &/or “silent” Where does a mutation have to be in order to be passed on to the next generation? Sex and Gamete cells Do questions #1-4 (p43-44) Read the “Living with Gaucher’s Disease” article and Sandy’s Story and answer questions #1-5 p46
