* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Mathematical Tools for Understanding Genome Rearrangements
Nutriepigenomics wikipedia , lookup
Human genetic variation wikipedia , lookup
Genetic engineering wikipedia , lookup
Genome (book) wikipedia , lookup
Epigenomics wikipedia , lookup
Nucleic acid double helix wikipedia , lookup
DNA supercoil wikipedia , lookup
Whole genome sequencing wikipedia , lookup
Molecular cloning wikipedia , lookup
Epigenetics of neurodegenerative diseases wikipedia , lookup
Public health genomics wikipedia , lookup
Cre-Lox recombination wikipedia , lookup
Designer baby wikipedia , lookup
Cancer epigenetics wikipedia , lookup
DNA damage theory of aging wikipedia , lookup
Cell-free fetal DNA wikipedia , lookup
Artificial gene synthesis wikipedia , lookup
Genealogical DNA test wikipedia , lookup
Frameshift mutation wikipedia , lookup
Deoxyribozyme wikipedia , lookup
No-SCAR (Scarless Cas9 Assisted Recombineering) Genome Editing wikipedia , lookup
Human genome wikipedia , lookup
Pathogenomics wikipedia , lookup
Mitochondrial DNA wikipedia , lookup
Extrachromosomal DNA wikipedia , lookup
Genomic library wikipedia , lookup
Metagenomics wikipedia , lookup
Minimal genome wikipedia , lookup
Genome editing wikipedia , lookup
Koinophilia wikipedia , lookup
Site-specific recombinase technology wikipedia , lookup
Non-coding DNA wikipedia , lookup
Oncogenomics wikipedia , lookup
History of genetic engineering wikipedia , lookup
Point mutation wikipedia , lookup
Microevolution wikipedia , lookup
Office of Research & Sponsored Programs Faculty / Academic Staff FORUM Fall 2012 Series Mathematical Tools for Understanding Genome Rearrangements presented by Manda Riehl Mathematics Wednesday September 19, 2012 12:10 - 12:50 p.m. *CETL (OL 1142)* The diversity of life is a direct result of inaccuracy in DNA replication. At some point in the past, humans and mice had a common ancestor, and many "mistakes" later, we have two apparently very different species. At the level of DNA, the evolutionary distance between organisms can be estimated by calculating the degree of disorder between the genes in different genomes. I will discuss a few of the ways that mathematicians have approached the problem of finding out how "different" different genomes are, and I will also describe a new model for mutations that I am researching that was developed for understanding mutations that cause human diseases. Feel free to bring your own lunch.