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Transcript
Psychgene Copy number variations and endophenotypes in psychiatric disorders Project target • Identify DNA-abboration (mutation) as reason for mood disorders. • Especially researched: – Schizophrenia (SZ) – Bipolar disorder (BD) – Major depression (MD) CNV (Copy number variation) • Alternations in the DNA make-up • Abnormal number of copies in one section of DNA • Up to 4 copies SNP (Single nucleotide polimorphism) • Similar to CNV • Not in the same section of DNA • On different chromosomes Candidate genes • Probably associated to genetic diseases • Healthy parents genes compared to diseased child’s • Healthy persones compared to diseased patients. Thank you for your attention
