Download Life of a Protein #1 This outline describes the job of a specialized

Life of a Protein #1
This outline describes the job of a specialized cell in the human body.
Determine 1) the cells location in the human body and 2) its job description from these clues.
The NUCLEUS gets a signal.
Genes in the NUCLEUS that code for specialized proteins are activated.
Messanger RNA is produced in the NUCLEUS.
mRNA travels to the cytoplasm through NUCLEAR PORES.
RIBOSOMES are produced by the NUCLEOLUS.
RIBOSOMES move to and attach to the ROUGH ENDOPLASMIC RETICULUM (ER).
RIBOSOMES on the ROUGH-ER binds to the mRNA and translates the code in the mRNA
sequence into a chain of amino acids (the primary structure of the proteins).
Finished amino acid strands are transferred to the lumen of the ROUGH-ER.
Amino acid chains are modified and folded inside the ROUGH ER into secondary and tertiary
structures.
The proteins are transported via VESICLES to the GOLGI APPARATUS.
At the GOLGI APPARATUS, the proteins are further modified with the addition of
carbohydrates.
The proteins are loaded into GOLGI SECRETORY VESICLES.
These GOLGI SECRETORY VESICLES also synthesize lactose. These VESICLES are
impermeable to lactose, so the lactose stays inside the VESICLE.
The VESICLES are full of stuff (high concentration of proteins and lactose). Water rushes into
the VESICLES due to osmosis (we will cover osmosis in this lecture).
GOLGI SECRETORY VESICLES swell with water, proteins, and lactose.
The GOLGI SECRETORY VESICLES move to the PLASMA MEMBRANE.
The water, proteins, and lactose exit the CELL via EXOCYTOSIS into a duct.
Milk duct
Cells location:___________________
Produce protein for
breast milk
Cells job:_______________________
Casein protein
Protein:________________________
Life of a Protein #2
This outline describes the job of a specialized cell in the human body.
Determine 1) the cells location in the human body and 2) its job description from these clues.
Epithelial cells release proteins, which communicate to our cell through the PLASMA
MEMBRANE.
The NUCLEUS gets the signal.
Genes in the NUCLEUS that code for specialized proteins are activated.
Messanger RNA is produced in the NUCLEUS.
mRNA travels to the cytoplasm through NUCLEAR PORES.
RIBOSOMES are produced by the NUCLEOLUS.
RIBOSOMES move to and attach to the ROUGH ENDOPLASMIC RETICULUM (ER).
RIBOSOMES on the ROUGH-ER binds to the mRNA and translates the code in the mRNA
sequence into a chain of amino acids, the primary structure of the proteins.
Finished amino acid strands are transferred to the lumen of the ROUGH-ER.
Amino acid chains are modified and folded inside the ROUGH ER into secondary and tertiary
structures.
The proteins are transported via VESICLES to the GOLGI APPARATUS.
At the GOLGI APPARATUS, the proteins are packaged in the GOLGI SECRETORY
VESICLES.
The GOLGI SECRETORY VESICLES move to the PLASMA MEMBRANE.
The proteins exit the CELL via EXOCYTOSIS, but stay attached to the outside of the
PLASMA MEMBRANE.
The proteins sticking out from the CELL MEMBRANE and attach to proteins sticking out from
the epithelial cells.
Blood vessel
Cells location:___________________
Produce protein to stop
cell movement
Cells job:_______________________
White blood cell
Type of cell:____________________