Download Lab 11 Nervous System I

Lab 11
Nervous System I
Laboratory Objectives
Describe the organization of the nervous system.
Identify the structure and function of the neuroglia.
Identify the differences between glial cells in the central nervous system and in the
peripheral nervous system.
Identify the structures of a typical neuron
Compare the location and function of the neuronal shapes.
Describe the mechanisms required to establish a resting membrane potential.
Identify the components of a synapse.
Compare impulse propagation for action potentials vs graded potentials.
State the rules for summation of EPSPs and IPSPs on a neuron which may have
thousands of inputs.
Name the features of the neuronal membrane that result in the action potential.
Compare factors relating to the speed of impulse propagation.
Identify signs and symptoms of a patient which suggest a problem with nerve
conduction.
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Activity 1: Structure and Function of the Nervous System
Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16: Nervous Tissue > See >
Animation: Introduction to Structure and Function of the Nervous System > sections: 1.1,
2.1-2.3, 3.1-3.5
1. Compare and contrast the following terms: afferent, efferent, sensory, motor,
ascending, and descending.
2. What is the function of an association neuron?
3. Using the following, diagram the organization of the nervous system: central
nervous system, peripheral nervous system, brain, spinal cord, somatic nervous
system, autonomic nervous system, and enteric nervous system.
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Activity 2: Neuroglia
Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16: Nervous Tissue > Do >
Activity 1: Table 16.1 Neuroglia
1. An immune process that results in demyelination of neurons in the CNS, would
result in the destruction of which glial cells?
2. An immune process that results in demyelination of neurons in the PNS, would
result in the destruction of which glial cells?
3. Dysfunction of which glial cell would decrease the production of cerebrospinal
fluid (CSF)?
4. Which glial cell controls permeability of the capillaries within the CNS?
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Activity 3: Paint a Neuron
Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16: Nervous Tissue > Do >
Interactive Exercise: Paint a Neuron
1. Compare the location, structure, and function of multipolar versus bipolar
neurons.
2. Which neuron structure releases neurotransmitter?
3. Which neuron structure receives information from other neurons?
4. Which neuron structure transmits information from the cell body?
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Activity 4: Resting Membrane Potential
Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16: Nervous Tissue > Do >
Interactive Exercise: Keep the Resting Membrane Potential
1. What is the main extracellular cation?
2. What is the main intracellular anion?
3. Will the outflow of potassium make the inside of the membrane more negative or
positive?
4. Why is the average resting membrane potential closer to the equilibrium potential
of potassium?
5. Which active transport process maintains the resting membrane potential?
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Activity 5: Graded Membrane Potentials
Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16: Nervous Tissue > Do >
Interactive Exercise: Are Your Synapses Working?
1. Compare temporal and spatial summation.
2. Release of neurotransmitter from the presynaptic neuron results from the inflow
of which extracellular cation?
Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16: Nervous Tissue > Do >
Interactive Exercise: Summation Smash
3. The binding of a neurotransmitter to a ligand-gated channel results in the inflow
of sodium into the cell. What effect does this have on the post-synaptic membrane?
4. The binding of a neurotransmitter to a ligand-gated channel results in the outflow
of potassium from the cell. What effect does this have on the post-synaptic
membrane?
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Activity 6: Action Potential
Navigation: WileyPlus > Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16:
Nervous Tissue > See > The Nervous System. Membrane Potentials > sections 5.1-5.2
1. Describe the cell membrane conditions associated with a resting membrane
potential.
2. What is the refractory period of a neuron?
Navigation: WileyPlus > Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16:
Nervous Tissue > Do > Interactive Exercise: Define Stages of the Action Potential
1. What is the result of a sub-threshold depolarization at the trigger zone?
2. Are sodium channels activated or inactivated during the absolute refractory
period?
3. Inactivation of sodium channels and opening of potassium channels has what
effect of the membrane?
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Activity 7: Neuron Impulse Propagation
Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16: Nervous Tissue > Do >
Interactive Exercise: Speed Up Nerve Impulse Propagation
1. Increasing the diameter of a neuron will have what effect on conduction?
2. Decreasing temperature will have what effect on conduction?
3. Myelination has what effect on neuron conduction?
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Activity 8: The Case of the Girl with On and Off Symptoms
Navigation: WileyPlus > Read, Study, & Practice > Lab Exercise 16: Nervous Tissue > Do >
Homeostatic Imbalance: The Case of the Girl with On and Off Symptoms
1. Which of the following best describes the patient’s problem? Why?
a. Disorder of impulse formation
b. Disorder of impulse conduction
c. Disorder of neurotransmitter formation
d. Disorder of astrocytes
2. Relate how the name of this disorder corresponds to the tissue changes in the
CNS.
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