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Name ________________________________ Date _________________ Period _____________________ RNA and Protein Synthesis Notes Organizer 1. What is the central dogma of Biology? 2. RNA, like DNA, is a nucleic acid made of nucleotides. What are the four differences between DNA and RNA? a. b. c. d. 3. Describe the functions of the three types of RNA molecules. a. mRNA – b. rRNA – c. tRNA – 4. Transcription: ______________ ______________ 5. What is transcription? 6. Where does transcription occur in the cell? 7. DNA must first be “read” and transcribed by RNA because: 8. Following transcription, what would be the complementary mRNA sequence to this strand of DNA? a. DNA: AGC TCC GAT GCA TAC TTG CCA 9. A ____________________ is a 3 base mRNA sequence that codes for a particular ________________________. a. There are _______________ different amino acids. b. Amino acids join together to form _________________________________. 10. Translation: ______________ ______________ 11. What is translation? 12. Where does translation occur in the cell? 13. Describe the overall process of translation: a. b. c. d. e. f. 14. The tRNA ________________________ ensures that the right amino acid is added to the chain. 15. Label the process of translation: 16. What is a mutation? 17. Describe the two types of mutations. a. Gene mutations: b. Chromosomal mutations: 18. Mutations that occur in somatic cells are ____________ passed on to the next generation. 19. Mutations that occur in sex cells are passed on and will be present in ______________ cell in the offspring. 20. Point mutations involve the changing of ________________ nitrogen base. a. Substitution: 21. Frameshift mutations alter the “reading frame” of the genetic code. a. Insertion: b. Deletion: 22. Use the following sentence to illustrate substitution, insertion, and deletion mutations: THE BIG FAT CAT ATE THE WET RAT a. Substitution: b. Insertion: c. Deletion: Test your knowledge of the following processes by placing the descriptions in the correct box. Keep in mind, you may use each phrase more than once! DNA mRNA mRNA Proteins Protein Synthesis DNA DNA Occurs in the nucleus Occurs in the ribosome Allows the “genetic message” to leave the nucleus RNA Polymerase DNA DNA Helicase DNA Polymerase Amino acids join together to form proteins mRNA Replication Copying of DNA for cell division rRNA tRNA Transcription Peptide Bonds Codon Anticodon Translation