Regulation of the phosphotransferase system (PTS)
... pgi, encoding the enzyme phosphoglucoisomerase, is a promising approach for strain improvement. It blocks the first step of glycolysis and directs the glucose-derived carbon flux towards the NADPHproducing pentose phosphate pathway. However, despite that C. glutamicum Δpgi grows well with sucrose as ...
... pgi, encoding the enzyme phosphoglucoisomerase, is a promising approach for strain improvement. It blocks the first step of glycolysis and directs the glucose-derived carbon flux towards the NADPHproducing pentose phosphate pathway. However, despite that C. glutamicum Δpgi grows well with sucrose as ...
Towards functional effects of polyphenols : modulation of energy
... A diet rich in fruits and vegetables contains high levels of polyphenols (up to 1 gram per day). Epidemiological studies suggest that a high dietary intake of selected polyphenols can be protective against development of cardiovascular heart diseases in humans. In addition, mechanistic studies demon ...
... A diet rich in fruits and vegetables contains high levels of polyphenols (up to 1 gram per day). Epidemiological studies suggest that a high dietary intake of selected polyphenols can be protective against development of cardiovascular heart diseases in humans. In addition, mechanistic studies demon ...
Fatty Acid-Mediated Quorum Sensing Systems Stenotrophomonas maltophilia DOCTORAL THESIS
... 4.1.1 Two variants of rpf cluster with main differences in rpfF and rpfC genes are distributed among S. maltophilia population. ......................................................... 48 4.1.2 RpfC-1 but not RpfC-2 contains a transmembrane sensor input domain highly related to the Xcc RpfH-RpfC co ...
... 4.1.1 Two variants of rpf cluster with main differences in rpfF and rpfC genes are distributed among S. maltophilia population. ......................................................... 48 4.1.2 RpfC-1 but not RpfC-2 contains a transmembrane sensor input domain highly related to the Xcc RpfH-RpfC co ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... the genotype of Helicobacter pylori in the population. Helicobacter pylori possess several virulence factors that play important role in the development of gastric diseases such as chronic gastric inflammation, ulcerative peptic diseases, gastric cancer and MALT-lymphoma [1]. There are many virulenc ...
... the genotype of Helicobacter pylori in the population. Helicobacter pylori possess several virulence factors that play important role in the development of gastric diseases such as chronic gastric inflammation, ulcerative peptic diseases, gastric cancer and MALT-lymphoma [1]. There are many virulenc ...
Identification and Cloning of a Cryptococcal Deacetylase That
... The structure and antigenic properties of individuai MP components have been only partially characterized (4,5). A 98-kDa MP, with homology to chitin deacetylases, was recently cloned and shown to stimolate a mouse CD4+-T-cell hybridoma to produce interleukin 2 (18). Mandel et al. cloned a cryptococ ...
... The structure and antigenic properties of individuai MP components have been only partially characterized (4,5). A 98-kDa MP, with homology to chitin deacetylases, was recently cloned and shown to stimolate a mouse CD4+-T-cell hybridoma to produce interleukin 2 (18). Mandel et al. cloned a cryptococ ...
Carnitine metabolism and biosynthesis in yeast Saccharomyces
... carnitine/acylcarnitine transporters, and is reasonably well studied and understood. While this function remains the only metabolically well established role of carnitine, several studies have been reporting beneficial effects associated with dietary carnitine supplementation, and some of those bene ...
... carnitine/acylcarnitine transporters, and is reasonably well studied and understood. While this function remains the only metabolically well established role of carnitine, several studies have been reporting beneficial effects associated with dietary carnitine supplementation, and some of those bene ...
Multiple sequence alignment for phylogenetic purposes
... of the protein databases), for a set of six species for which the protein structures are known (Fig. 1). The average pairwise amino-acid identity among the six full sequences is 21%, which is within what is known as the ‘twilight zone’ of protein similarity, where sequence alignment can be very prob ...
... of the protein databases), for a set of six species for which the protein structures are known (Fig. 1). The average pairwise amino-acid identity among the six full sequences is 21%, which is within what is known as the ‘twilight zone’ of protein similarity, where sequence alignment can be very prob ...
CYP 2D6 Polymorphism
... CYP 2C19 individuals with inactive enzyme (3-6 % of the caucasian and 15-20 % of the asian population) CYP 2D6 poor metabolizers in 5-8 % of the european, 10 % of the caucasian, and <1% of the japanese population. Over expression (gene duplication) among parts of the african and oriental population. ...
... CYP 2C19 individuals with inactive enzyme (3-6 % of the caucasian and 15-20 % of the asian population) CYP 2D6 poor metabolizers in 5-8 % of the european, 10 % of the caucasian, and <1% of the japanese population. Over expression (gene duplication) among parts of the african and oriental population. ...
Cytochrome P450 and Polymorphism - uni
... (CAR) is found in the cytoplasm and dimerizes with PXR in the nucleus. Analog to PXR, the CYP2B gene is regulated. Likewise high sequence homology has been found for the vitamine D receptor (VDR) that regulates CYP27, and for the arylhydrocarbon receptor (AHR) (dioxin receptor). ...
... (CAR) is found in the cytoplasm and dimerizes with PXR in the nucleus. Analog to PXR, the CYP2B gene is regulated. Likewise high sequence homology has been found for the vitamine D receptor (VDR) that regulates CYP27, and for the arylhydrocarbon receptor (AHR) (dioxin receptor). ...
Identification and first characterization of pairing
... Furthermore, it has been shown, that females induce lipid accumulation and lipase activity in males (Haseeb et al., 1989). However, research on a factor transferred from the female to the male was neglected as it was assumed to be uncertain and less promising concerning schistosomiasis control compa ...
... Furthermore, it has been shown, that females induce lipid accumulation and lipase activity in males (Haseeb et al., 1989). However, research on a factor transferred from the female to the male was neglected as it was assumed to be uncertain and less promising concerning schistosomiasis control compa ...
Molecular characterization of a cluster of at least two
... streptococci. Sequence alignment also indicated that gtfK lay very close to and downstream from gtfJ, and that both were transcribed in the same direction. ...
... streptococci. Sequence alignment also indicated that gtfK lay very close to and downstream from gtfJ, and that both were transcribed in the same direction. ...
Molecular characterization of a cluster of at least two
... streptococci. Sequence alignment also indicated that gtfK lay very close to and downstream from gtfJ, and that both were transcribed in the same direction. ...
... streptococci. Sequence alignment also indicated that gtfK lay very close to and downstream from gtfJ, and that both were transcribed in the same direction. ...
Catabolism and biotechnological applications of cholesterol
... Cholesterol is frequently found in the biosphere, not only because of its natural abundance, but also due to its high resistance to microbial degradation. Cholesterol is a recalcitrant molecule to biodegradation because of its low number of functional groups (one CC double bond and a single hydroxyl ...
... Cholesterol is frequently found in the biosphere, not only because of its natural abundance, but also due to its high resistance to microbial degradation. Cholesterol is a recalcitrant molecule to biodegradation because of its low number of functional groups (one CC double bond and a single hydroxyl ...
Auxin: Regulation, Action, and Interaction
... permanently inactivate IAA, plants can employ conjugation and direct oxidation. Consistent with its definition as a hormone, IAA can be transported the length of the plant from the shoot to the root; this transport is necessary for normal development, and more localized transport is needed for tropi ...
... permanently inactivate IAA, plants can employ conjugation and direct oxidation. Consistent with its definition as a hormone, IAA can be transported the length of the plant from the shoot to the root; this transport is necessary for normal development, and more localized transport is needed for tropi ...
c12) United States Patent - Rice Scholarship Home
... The ratio of the reduced to oxidized form of this cofactor, the NADH/NAD+ ratio, is critical for the cell. The NAD(H/+) cofactor pair is very important in microbial catabolism, where a carbon source, such as glucose, is oxidized through a series of reactions utilizing NAD+ as a cofactor and producin ...
... The ratio of the reduced to oxidized form of this cofactor, the NADH/NAD+ ratio, is critical for the cell. The NAD(H/+) cofactor pair is very important in microbial catabolism, where a carbon source, such as glucose, is oxidized through a series of reactions utilizing NAD+ as a cofactor and producin ...
Elucidating Flux Regulation of the Fermentation Modes of
... friends in Hong Kong as well as in Denmark who show their love and care constantly which are vital for me to face the live and challenges in Denmark. A person of paramount importance to me who I must thank most deeply is my wife, Sandy Wong, who has accompanied me to have a new life here and has alw ...
... friends in Hong Kong as well as in Denmark who show their love and care constantly which are vital for me to face the live and challenges in Denmark. A person of paramount importance to me who I must thank most deeply is my wife, Sandy Wong, who has accompanied me to have a new life here and has alw ...
Nucleic acid vaccines for ehrlichia chaffeensis and methods of use
... disease caused by members of the tribe Ehrlichiae have been described. Ehrlichiae infect leukocytes and endothelial cells of many different mammalian species, some of them causing serious human and veterinary diseases. Over 400 cases of ...
... disease caused by members of the tribe Ehrlichiae have been described. Ehrlichiae infect leukocytes and endothelial cells of many different mammalian species, some of them causing serious human and veterinary diseases. Over 400 cases of ...
Mechanisms underlying inhibition of muscle disuse
... mammals, muscle disuse atrophy has been associated with oxidative damage due to increased mitochondrial ROS production. C. alboguttata reduced skeletal muscle mitochondrial respiration by approximately 50% following four months of aestivation, while mitochondrial ROS production was more than 80% lo ...
... mammals, muscle disuse atrophy has been associated with oxidative damage due to increased mitochondrial ROS production. C. alboguttata reduced skeletal muscle mitochondrial respiration by approximately 50% following four months of aestivation, while mitochondrial ROS production was more than 80% lo ...
Xenopus Spinal Neurons Express Kv2 Potassium Channel
... yielding only one amino acid change (Fig. 1B). Because most of the nucleotide differences between the PCR products and the library cDNAs conserve the ainino acid sequence, it is unlikely that the PCR variants are attributable to random errors introduced by reverse transcriptase or Taq polymerase. It ...
... yielding only one amino acid change (Fig. 1B). Because most of the nucleotide differences between the PCR products and the library cDNAs conserve the ainino acid sequence, it is unlikely that the PCR variants are attributable to random errors introduced by reverse transcriptase or Taq polymerase. It ...
Renal Drug Metabolism - Pharmacological Reviews
... either in whole kidney or in cortical tissue, biotransformations have also been identified in the medullary region (Toback et al., 1977a; Lohr and Acara, 1990). Information accumulated over the past 20 years demonstrates a large capacity for metabolism in the kidney, leading to activation or inactiv ...
... either in whole kidney or in cortical tissue, biotransformations have also been identified in the medullary region (Toback et al., 1977a; Lohr and Acara, 1990). Information accumulated over the past 20 years demonstrates a large capacity for metabolism in the kidney, leading to activation or inactiv ...
Characterization of Agouti-Related Protein
... Agouti-related protein (AGRP) is a naturally occurring antagonist of melanocortin action that is thought to play an important role in the hypothalamic control of feeding behavior. The exact mechanism of AGRP and Agouti protein action has been difficult to examine, in part because of difficulties in ...
... Agouti-related protein (AGRP) is a naturally occurring antagonist of melanocortin action that is thought to play an important role in the hypothalamic control of feeding behavior. The exact mechanism of AGRP and Agouti protein action has been difficult to examine, in part because of difficulties in ...
Chapter 4 - University of Amsterdam
... mitochondria. Additional (related) roles of carnitine include modulation of the acylCoA/CoA ratio, storage of energy (in the form of acetyl-carnitine) and excretion of poorly metabolizable, toxic, acyl groups (4). In animal species, carnitine uptake by food is thought to be an important contributor ...
... mitochondria. Additional (related) roles of carnitine include modulation of the acylCoA/CoA ratio, storage of energy (in the form of acetyl-carnitine) and excretion of poorly metabolizable, toxic, acyl groups (4). In animal species, carnitine uptake by food is thought to be an important contributor ...
Functional and Biochemical Analysis of Glucose-6
... (NADPH), a very important reducing agent that confers protection against cellular oxidative stress and helps in the regeneration of oxidized glutathione (GSSG). The primary and tertiary structure of human G6PD has been determined from the nucleotide sequence of full-length cDNA clones and by crystal ...
... (NADPH), a very important reducing agent that confers protection against cellular oxidative stress and helps in the regeneration of oxidized glutathione (GSSG). The primary and tertiary structure of human G6PD has been determined from the nucleotide sequence of full-length cDNA clones and by crystal ...
The Protein Cevalently Linked to the 5'... of Poliovirus RNA by Victor Robert Ambros
... been particularly inspirational to me in various ways and have helped me maintain my excitement for science. These include Edward Gruberg, Jerome Lettvin, Lan Bo Chen, Ethan Signer, Daniel Kemp, and Hans Lucas Tueber. Most of all, I am very grateful to Candy for her unfailing help and advice. ...
... been particularly inspirational to me in various ways and have helped me maintain my excitement for science. These include Edward Gruberg, Jerome Lettvin, Lan Bo Chen, Ethan Signer, Daniel Kemp, and Hans Lucas Tueber. Most of all, I am very grateful to Candy for her unfailing help and advice. ...
Analysis and engineering of acetyl
... Chapter 3 also refiealed targets that need to be addressed to achiefie optimal in vivo performance of the alternatifie reactions for sffpply of cytosolic acetyl-CoA. Design and implementation of metabolic engineering strategies to improfie ffffies toflards precffrsors not only reqffires knoflledge of ffffi distribff ...
... Chapter 3 also refiealed targets that need to be addressed to achiefie optimal in vivo performance of the alternatifie reactions for sffpply of cytosolic acetyl-CoA. Design and implementation of metabolic engineering strategies to improfie ffffies toflards precffrsors not only reqffires knoflledge of ffffi distribff ...
Endogenous retrovirus
Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.