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Transcript
Unit 4: I Got It From My Momma
DNA Replication
Name _______________________________________________
Date ________________ Period _______ Assignment 48
DNA Review
Notes
What is DNA Replication?
 DNA replication occurs when _______________________________________________________________________
 Replication produces _________ new strands of DNA that are _____________________________________________
1st Step
 Base pairs ________________________________ & 2 ________________________________
 Individual strands becomes ___________________ for a new strand of DNA
2nd Step
 DNA polymerase ________________________________ to each template & ________________________________
– ______ with ______
– ______ with ______
rd
3 Step
 The result is ____________________________________________ which are exact copies of each other
 Each DNA molecule has ____________________________________________
Why is Replication Important?
 DNA replication happens when ______________________________________________________________________
 It is important that DNA replication happens because it allows each new cell to have DNA
 DNA replication allows a cell to ______________________________________________________________________
Practice
Instructions: Fill in the blank or circle the word or phrase that best completes the statement.
1.DNA replication is the process by which DNA is (copied / observed) during the cell cycle.
2.DNA replication takes place in the (centrosome / nucleus) of a eukaryotic cell.
3.DNA replication needs to occur so that every (cell / organism) will have a complete set of DNA following cell division.
4.DNA polymerase has a proofreading function that enables it to detect (errors / enzymes) and correct them.
5.DNA replication occurs (before / after) cell division.
6.Where is DNA located inside the cell? So, where in the cell does DNA replication occur?
7.If a strand of DNA has the sequence T A G G T A C, write down the sequence of the parallel DNA strand.
8.If a strand of DNA has the sequence C G A T C G G T T A, write down the sequence of the parallel DNA strand.
9.In order for the DNA strands to separate, the ________________ bonds connecting the base pairs must be broken.
10. DNA replication is semi-conservative because each molecule includes 1 _________ strand and 1 _________ strand.
Instructions: Use page 223 to draw and label a diagram showing each step of replication.
_______________
_______________
_______________
_______________
11. On the diagram to the right, draw arrows to label the new and old strands of DNA.
12. Sequence the steps of DNA replication below from 1 - 6.
a) _____ Free nucleotides pair with open nucleotides
b) _____ An enzyme proofreads to check for replication errors
c) _____ Weak hydrogen bonds are broken by enzymes
d) _____ 2 identical strands of DNA are produced
e) _____ DNA molecule “unzips”
f) _____ Enzymes “zip” up the newly synthesized DNA molecule
_______________
_______________