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Unit 4: I Got It From My Momma DNA Replication Name _______________________________________________ Date ________________ Period _______ Assignment 48 DNA Review Notes What is DNA Replication? DNA replication occurs when _______________________________________________________________________ Replication produces _________ new strands of DNA that are _____________________________________________ 1st Step Base pairs ________________________________ & 2 ________________________________ Individual strands becomes ___________________ for a new strand of DNA 2nd Step DNA polymerase ________________________________ to each template & ________________________________ – ______ with ______ – ______ with ______ rd 3 Step The result is ____________________________________________ which are exact copies of each other Each DNA molecule has ____________________________________________ Why is Replication Important? DNA replication happens when ______________________________________________________________________ It is important that DNA replication happens because it allows each new cell to have DNA DNA replication allows a cell to ______________________________________________________________________ Practice Instructions: Fill in the blank or circle the word or phrase that best completes the statement. 1.DNA replication is the process by which DNA is (copied / observed) during the cell cycle. 2.DNA replication takes place in the (centrosome / nucleus) of a eukaryotic cell. 3.DNA replication needs to occur so that every (cell / organism) will have a complete set of DNA following cell division. 4.DNA polymerase has a proofreading function that enables it to detect (errors / enzymes) and correct them. 5.DNA replication occurs (before / after) cell division. 6.Where is DNA located inside the cell? So, where in the cell does DNA replication occur? 7.If a strand of DNA has the sequence T A G G T A C, write down the sequence of the parallel DNA strand. 8.If a strand of DNA has the sequence C G A T C G G T T A, write down the sequence of the parallel DNA strand. 9.In order for the DNA strands to separate, the ________________ bonds connecting the base pairs must be broken. 10. DNA replication is semi-conservative because each molecule includes 1 _________ strand and 1 _________ strand. Instructions: Use page 223 to draw and label a diagram showing each step of replication. _______________ _______________ _______________ _______________ 11. On the diagram to the right, draw arrows to label the new and old strands of DNA. 12. Sequence the steps of DNA replication below from 1 - 6. a) _____ Free nucleotides pair with open nucleotides b) _____ An enzyme proofreads to check for replication errors c) _____ Weak hydrogen bonds are broken by enzymes d) _____ 2 identical strands of DNA are produced e) _____ DNA molecule “unzips” f) _____ Enzymes “zip” up the newly synthesized DNA molecule _______________ _______________