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Warm-up When do you think DNA needs to replicate in a cell? DNA Replication 1. Rapid a. In bacteria, 500 nucleotides are added per second. b. In human cells, it takes only a few hours to copy the 6 billion bases. 2. Accurate Only about 1 in a billion base pairs is incorrectly paired. Steps of Replication 1. The strands unzip and unwind with the help of several enzymes. 2. Proteins bond to specific sites on DNA called origins of replication. 3. DNA polymerase moves down the strands, inserting the correct base to pair with each half of DNA molecule. 4. “Proofreading enzymes” double check the new strands, then the strands “zip up” and two new DNA molecules are present. DNA Extraction Lab