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Jeopardy Eukaryotic Genetics Interference RNA and mRNA 100 What does the “mi” in miRNA represent? 100 bonus: siRNA? 200 What protein breaks up RNA transcripts from miRNA-encoding genes? 300 What are the two results of miRNA binding to a target mRNA? 400 Describe the process of ubiquination. 400 bonus: ubiquination comes after which step in protein production? 500 Explain how mRNA can be stored for later use. 100 bonus: Give an example of this. Genomes 100 The faster method of genome sequencing. 100 Bonus: Who developed this method? 200 Describe how polyploidy results in gene duplication and new genes in a cell. 300 List the 3 steps in mapping an entire genome 300 Bonus: How many polymorphisms are typically on a chromosome? 400 Humans have how many α and β functional hemoglobins? 400 Bonus: nonfunctional nucleotide sequences? 500 How are cDNA libraries created? Cancer 100 special genes that code proteins that promote normal cell growth and division 100 Bonus: cells that inhibit cell growth 100 Bonus: what are cancer causing genes? 200 genes that when altered are responsible for more than 50% of all human cancers 200 Bonus: Acetylation allows what to occur? 300 cancer often comes from breaking and incorrect rejoining of what? 400 how does duplicating proto-oncogenes lead to cancer development? 500 Oncogenes were discovered by studying what organism? Miscellaneous 1 100 a heritable change in gene expression that isn’t based on base changes 200 explain how acetylation of histones causes DNA unfolding 300 human hemoglobin is in what protein structure? 400 heavily methylated dense DNA 500 What is the difference between liver and lens cells? Miscellaneous 2 100 DNA complex protein 200 histone tails—name and charge 300 subunits of histones 400 process of DNA modification that usually inactivates genes 500 name for tryptophan in its role with the trp operon Miscellaneous 3 100 direction of conjugation genetic transfer 200 DNA with inverted repeats 300 enzyme needed for lactose breakdown 400 genes that are turned on or off depending on the environment Jeopardy Eukaryotic Genetics 500 the name for taking many antibiotics at once to try to eliminate all resistant bacteria