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Download 20. Genes and chromosomes
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Genes and Chromosomes DNA molecules are the largest macromolecules in the cells and are commonly packed into structures called chromosomes. A single chromosome may carry thousand of genes Together, all of a cell’s gene and intergenic DNA (DNA between genes) is called GENOME Chromosome Genes introns – intervening sequences exons – coding sequences Eukaryotic chromosomes Supercoiling of DNA Plectonemic and solenoidal supercoiling. Nucleosome = histone + DNA Nucleosomes are packed in 30nm fiber Loops of 30nm fiber attached to nuclear scaffold
