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Name: DNA Biology I RNA . Protein Go to Mr. Mason’s site, and then to the link for “Genetics – DNA Replication/Protein Synthesis” 1. The first step in DNA replication is this: 2. What is it specifically that causes the DNA to “unzip”? 3. Try to match the bases (the letters) together to replicate the DNA strands. What do you notice about how the letters pair together? 4. Move on to “Protein Synthesis”. After unzipping the DNA, the process of transcription begins. What is the goal of this process? 5. What is different about how the bases pair together when making RNA? 6. After mRNA (messenger RNA) is made, what happens to it? 7. Our next step is translation. What happens during translation and where does this occur? 8. Match the amino acid anticodons with the mRNA codons. (Mr. Mason will explain what is happening here later…just play with it!) Get it? Good. Let’s take a test! OK…maybe you’re as confused as I would be at this point. Let’s try this again with a different site that explains it a little differently. Go to the link for “Genetics – Gene transcription/translation” 9. In the space above the DNA strand, use your keyboard to type in the correct bases. Remember what matches with G? Which base goes with T? (Remember, you’re making RNA here, not DNA) This is transcription. 10. When you understand what to do during translation, give it a shot. What is the RNA sequence and corresponding amino acid that starts translation every time? 11. What is the stop codon (RNA sequence) that ended the process of translation? What are the other possible stop codons? Get Mr. Mason’s initials here when finished: Explain transcription: Explain translation: Your Turn! Copy the following DNA strand: A A G C T T A C G G T A C C C A G G A T T A T G C C A Translate the following DNA strand into mRNA, and then translate the RNA into an amino acid sequence: DNA Strand A A T A C G U G C C A A A U G A A U G G A G A A U C U A A mRNA Amino Acid Chain