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It’s DNA
Or The
highway
Express your
Genes
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This!
Who did
that?
Potpourri
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The purine and pyrimidine
bases in DNA.
What are adenine, guanine,
thymine, and cytosine?
The term given for opposite
orientation of strand in the
DNA helix.
What is antiparallel?
The fragments of DNA that
are produced on the lagging
strand.
What are Okazaki fragments?
The enzyme that unwinds the
DNA helix during replication.
What is DNA helicase?
The enzyme that prevents
knots from forming in the DNA
as it is unravelling.
What is gyrase?
Introns and Exons
What are non-coding and
coding regions (respectively)
in DNA?
Regions on the tips of
chromosomes that are partly
eroded with each cell division.
What are telomeres?
Parts of an operon
What are the operator, the
promoter, and the gene?
Transcription is turned off by a
repressor in the lac operon
and is turned on if lactose is
present.
What is negative gene
regulation?
Tryptophan is an example of
this in the tryp operon in
E.Coli
What is a co-repressor?
The site on mRNA where the
ribosome attaches.
What is the 5’
methlyguanosine cap?
UAA, UAG, and UGA
What are stop codons?
Enzyme which forms bond
between tRNA and its amino
acid.
What is amino-acyl tRNA
synthase?
The enzyme which forms a
peptide bond between amino
acids during formation of the
polypeptide.
What is peptidyl transferase?
Amino acids in the
protein specified by
the following DNA
sequence:
3’ AGATTTCCGCTC 5’
What are serine, lysine,
glycine, and glutamate?
Using mice and two strains of
bacteria, he proved that it is
possible for bacteria to take
up genetic material from other
bacteria and be transformed.
Who is Griffith?
Their work on X-ray diffraction
and nucleic acids showed DNA
likely had a helix-type shape.
Who are Rosalind Franklin and
Maurice Wilkins?
They proved that DNA is the
genetic material and not
proteins by experiments with
radioactively labelled phages.
Who are Hershey and Chase?
He showed that the amounts
of guanine and cytosine was
the same in cells.
Who is Chargaff?
Discovered the concept of the
operon as a means of
controlling genes in
prokaryotes.
Who are Jacob and Monod?
Examples of these include
TATA box and CAAT box.
What are promoters?
How mRNA is modified in
eukaryotic cells.
What is removing introns,
adding 5’ methylguanosine
cap, and poly A tail?
Process which amplifies the
amount of DNA in a sample by
using the strands as a
template.
What is polymerase chain
reaction (PCR)?
Enzymes found in bacteria
that cut DNA at predictable
sequences.
What are restriction
endonucleases?
Process where a gene is
inserted into a bacterial
plasmid and introduced into
bacteria that produce the
protein product.
What is gene cloning?
FINAL JEOPARDY
Who discovered the structure
of DNA?
Who are James Watson and
Frances Crick?