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Transcript
BTY100-Lec#4.2
DNA to Protein (Central Dogma)
Created By:
Mamta Sharma
© LPU : BTY100
Outline
• Gene
• Central Dogma: DNA to Protein
– Replication
– Transcription
– Translation
© LPU : BTY100
GENE
A Gene is a segment of DNA and is located on the chromosome.
Gene specifies the structure of particular protein that make up
each cell.
© LPU : BTY100
Structure of Gene
 Composed of
 Exons
 Introns(absent in
prokaryotes)
 Control elements
© LPU : BTY100
Parts of Gene
Exon – Coding sequence
Intron – Non coding sequence
Only present in Eukaryotes!!
© LPU : BTY100
Central Dogma: DNA to Protein
© LPU : BTY100
DNA Replication
Process of producing two
identical replicas from one
original DNA molecule.
It occurs with the help of a lot
of enzymes/catalyst.
© LPU : BTY100
Transcription: Process of Formation of RNA
from DNA
© LPU : BTY100
TRANSLATION:
Process by which
RNA (mRNA) produced by
transcription is decoded by a
ribosome complex to produce a
protein
Example???.
© LPU : BTY100
TRANSLATION
© LPU : BTY100
Amino Acid Chain
© LPU : BTY100
Protein structure
Further Foldings
© LPU : BTY100
Next Class: Manipulating Genes
© LPU : BTY100