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BIOLOGY LECTURE -- CHAPTER 10 Protein Synthesis ▪ A. Importance of DNA ▪ ▸ “DE” ▸ “Oxy” === === – Cells have a Thread-like material called _____________________________ – This material thickens and forms __________________________________ –It is this material that is responsible for passing on the ________________________________information. ▪ CHROMOSOMES ARE MADE UP OF THE FOLLOWING: ▪ 1) ____________________________: ▸ – _______________________: Building blocks of Proteins (20 common) ▪ 2) __________________________: ▸ ▪Nucleic Acids make up NUCLEOTIDES, which built from the following 3 parts: ▸ -1- ▪____________--- ___________________________________________ ▸Describe the DNA molecule as being Spiral in Shape with the BASES on the inside and the Sugar- Phosphate Groups on the outside. ▪____________--▸ ____________________________________ (American Biologist) ▸ _____________________________________ (British Biophysicist) –They proposed the ____________________ for the structure of DNA ▪STRUCTURE OF DNA ▸1) ▸2) ▸3) ▸4) ▸5) ▸6) ▸7) Model proposed was in the shape of a __________________________ This ladder was twisted to form a ______________________________ The Sides of the ladder contained the ____________________________ The Rungs were _____________________________ The Sugar is a ______Carbon Sugar called ___________________________ To each Deoxyribose, there is a _____________________________________ connected. The Rungs are connected by weak ___________________________________ ▸DNA is built up of small units called __________________________________ (See earlier in notes) ▸Several million nucleotides may be found in a single DNA strand -2- DNA BASES ▪1) ▪2) ▸These are referred to as _______________________________________ ▪These Bases belong to 2 Organic Classes: ▸ 1) ▸ 2) –SEE OVERHEAD (HANDOUT) II. THE ROLES OF DNA AND RNA ▪ A. ▸ ▪3 Processes involved: ▸1) ▸2) ▸3) -3- ON BASE STRUCTURE ▪A T C G G C T T A T G C C A ▪----------------------------------------------------------▪ ▸ ▸ –This is what Replication is all about!! B. TRANSCRIPTION ▪Proteins are synthesized on the __________________________________ ▪With the help of Enzymes, The information of One strand of DNA is copied _____________________________ exactly. ▸This copy is called _______________________________________________ ▸_________________________________ is the process of transferring the information from DNA to RNA ▪3 Types of RNA: ▸1) _____________________________________ ---Carries genetic information from the Nucleus to the Ribosomes in the Cytoplasm ▸2) _____________________________________--- Carries the Amino Acids in the Cytoplasm to the Ribosomes ▸3) _____________________________________ -4- --- Is found in the Ribosomes HOW DOES A CELL MAKE MESSENGER RNA? ▪1) ▪2) ▪3) ▪4) DIFFERENCES BETWEEN DNA AND RNA: ▪1) ▪2) ▸ __________________________________________________________!!!!! ▪3) III. CODONS DETERMINE THE AMINO ACID SEQUENCE ▪There are 1000's of bases on an RNA strand, and they can occur in any order. ▪__________________________________ are not important to Protein Synthesis ▪______________________: This is a Group of 3 Bases. Also referred to as a _________________________ ▪____________Bases can combine to make ____________________3-Base Combinations -5- mRNA CODONS: ▪1) ▪2) ▪3) ▪4) ▪5) ▪6) ▪7) ▸*** ______________________________---> Gets the Sequence Started ▸*** ______________________________---> Stops the Sequence C. TRANSLATION ▪The actual process of bonding Amino Acids to form Proteins ▪REASON: ▸“Also Known As” --- ______________________________________ Transfer RNA: ▪Shaped like a _______________________ ▸One end has an attachment site for an _____________________________ ▸The other end is an Exposed Base Triplet called an ______________________ –ANTICODON: –EXAMPLES: -6-