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Transcript
Biology 12
Unit D - DNA
DNA Workshop
Go to my website at http://sd67.bc.ca/teachers/barcuri/ → Click on Biology 12 → course
outline → Unit D – DNA → DNA workshop assignment.
Open this assignment and use it to follow the links. This will make it easier than typing the
links in yourself. Your welcome!
Go to the following websites and answer the questions below.
http://caligula.bcs.deakin.edu.au/bcs_courses/forensic/Chemical%20Detective/DNA_Struct
ure.htm
The weight of DNA can range from __________ amu to _________________ amu.
What are the 3 basic units that make up a nucleotide?
What does the phosphate group look like?
Draw and name the four bases. Show all of the elements in each base.
Biology 12
Unit D - DNA
Which bases have double rings? _______________ and ________________
The single strands of DNA are wound together to form a ________________, the two
strands being held together by attractions, a called _____________ bonds, between the
bases attached to the _____________ - _______________ backbone.
Give the names of the bases that always match with the base given below.
Adenine: ______________
Cytosine: ___________________
Click on the link to The Function of DNA
DNA stores an organism's __________________ information and controls the production of
___________________ and is thus responsible for the _____________________ of an
organism.
Where is DNA normally found? ________________________
What are chromosomes? __________________________________________
The sections of chromosomes are called ___________
Protein is a polymer of amino acids. If one wrong amino acids is placed in the wrong order a
mutation cam occur. What condition occurs if the wrong amino acid is substituted in
haemoglobin? ______________________
What is the base sequence for this condition? ___________ - _________ - _________
Click on the link RFLP DNA Typing
What are the 4 parts to this procedure?
Biology 12
Unit D - DNA
Second Website: http://www.ucmp.berkeley.edu/glossary/gloss3/dna.html
If an entire molecule of DNA from a virus was the scale shown, the image would be
______________ high. For the bacteria, E.Coli, the image would be
___________________ long, and for a typical piece of DNA from a eukaryote cell, the
image would stretch for ________________________ .
How many times larger is the DNA in the eukaryote cell compared to the DNA in the virus
cell. ( You may need to do some math!)
Why do you think that it is so much longer? (Hint: What is the function of DNA exactly)
What force holds the 2 DNA strands together? _______________
What is the benefit to having hydrogen bonds, in regards to replication?
Click on the word BACTERIA in the second paragraph. What are 3 importance uses
of bacteria?
Click on the word VIRUS in the second paragraph. What does a virus do when it
comes into contact with a host cell?
What is the dormant phase of the viruses life called? _______________
Biology 12
Unit D - DNA
List 8 diseases that a virus can cause.
Third Website: http://www.pbs.org/wgbh/aso/tryit/dna/#
Read the Intro page
Click on: Go directly to DNA Workshop Activity
Click on DNA Replication – complete the reaction
Click on DNA replication

Once complete go back to the homepage and click on DNA Replication
List the 3 steps to DNA replication
1.
2.
3.
Only one mistake may exist in every __________ base pairs. That's the same as typing out
the entire Encyclopaedia Britannica five times and typing in a wrong letter only once!
At the bottom of this web page, click on All Wound Up
The DNA is wrapped around spools of a protein called _____________ .
Fourth Website:
http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/D/DNAReplication.html
What does the term semi-conservative imply?
Biology 12
Unit D - DNA
The single molecule of DNA in the bacteria, E. coli contains 4.7 x 106 nucleotide pairs. DNA
replication begins at a single, fixed location in this molecule, called the replication origin, it
proceeds at about _______ nucleotides per second, and thus is done in approximately
_____ minutes.
The average human chromosome contains 150 x 106 nucleotide pairs, which are copied at
about 50 base pairs per second. How long does it take to replicate? ________ . Why is it so
much faster?
Last but not least.
http://www.pbs.org/wgbh/nova/sheppard/analyze.html
This web site will allow you to use Gel electrophoresis to determine the sequence of some DNA and
help you solve a crime through DNA finger printing.
Read the intro page
Go to Part I – Read
Go to Part II - Read
If it says start over! You messed up and you must restart.