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Protein Synthesis Chapter 10 -4 Group 1: Flow of Genetic Information Read page 204 in you text and complete the following: 1. What is a gene? 2. What does a gene direct? 3. What does RNA stand for? 4. Define Transcription Translation Protein Synthesis 5. Explain DNA -> RNA -> protein synthesis 6. Draw diagram 10-2 label and explain Group 2: RNA Structure and Function Read page 205 in your text and complete the following: 1. List the four ways RNA differs from DNA 2. Describe the structure and function of mRNA 3. Describe the structure and function of rRna 4. Describe the structure and function of tRNA 5. Draw the figure 10-14 and label and explain Group 3: Transcription Read page 206 in your text and complete the following: 1. Where does transcription take place? 2. What is RNA polymerase? 3. What determines the RNA sequence of bases on a RNA strand 4. What is the base pair rule for RNA? 5. Given a strand of DNA : AATCGG what is the RNA strand 6. What happens when RNA polymerase reaches a termination signal? 7. Draw and explain figure 10-15 Group 4: The Genetic Code Read page 207 in your text and complete the following: 1. How are amino acids assembled 2. Define genetic code. 3. Define codon. 4. How does the genetic code support the idea that all organisms share common ancestry 5. Draw the table 10-1 Codons in mRNA and explain how it is used. Group 5: Translation Read pages 208 and 209 in your text and complete the following: 1. What are polypeptides? 2. What are peptide bonds? 3. How many different amino acids are there? 4. Describe the five steps of translation 5. What is an anticodon? Group 6: The Human Genome Read page 210 in your text and the other supplemental reading provided by your teacher and complete the following: 1. What is a genome? 2. How many make up the human genome? 3. What is a gene? 4. What happens if DNA is mutated? 5. When was the human genome project? 6. How is the human genome being used? 7. Draw a chromosome like the one attached. List just a few genes and locations to give the class how the human genome looks A Brief Guide to Genomics An organism's complete set of DNA is called its genome. Virtually every single cell in the body contains a complete copy of the approximately 3 billion DNA base pairs, or letters, that make up the human genome. With its four-letter language, DNA contains the information needed to build the entire human body. A gene traditionally refers to the unit of DNA that carries the instructions for making a specific protein or set of proteins. Each of the estimated 20,000 to 25,000 genes in the human genome codes for an average of three proteins. Located on 23 pairs of chromosomes packed into the nucleus of a human cell, genes direct the production of proteins. If a cell's DNA is mutated, an abnormal protein may be produced, which can disrupt the body's usual processes and lead to a disease, such as cancer. The Human Genome Project The Human Genome Project, which was led at the National Institutes of Health, produced a very high-quality version of the human genome sequence completed in April 2003, all 23 chromosome’s genes have been located and identified like the one attached. The Human Genome Project was designed to generate a resource that could be used for a broad range of biomedical studies. One such use is to look for the genetic variations that increase risk of specific diseases, such heart disease, diabetes, blindness, and cancer. Genome-based research is already enabling medical researchers to develop more effective diagnostic tools, to better understand the health needs of people based on their individual genetic make-ups, and to design new treatments for disease.