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Transcript
TISSUES DEPENDENT ON ANAEROBIC GLYCOLYSIS
Many tissues, including red blood cells, the kidney medulla, the tissues of the eye,
and skeletal muscles, rely on anaerobic glycolysis for at least a portion of their ATP
requirements .
The lack of mitochondria, or the increased rate of glycolysis, is often related to some
aspect of cell function.
For example, the mature red blood cell has no mitochondria because oxidative
metabolism might interfere with its function in transporting oxygen bound to
hemoglobin.
Some of the lactic acid generated by anaerobic glycolysis in skin is secreted in sweat,
where it acts as an antibacterial agent.
Many large tumors use anaerobic glycolysis for ATP production, as they lack blood
capillaries for oxygen supply in their core.