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In eukaryotes, cell division occurs in 2 major stages. 1. Mitosis: cell nucleus divides (exact copy made) 2. Cytokinesis: division of the cell cytoplasm. Cyto = cell kinesis = movement cytoplasm cytoskeleton pyrokinesis telekinesis Chromosomes: How genetic information is passed from one generation to the next. Before cell division, each chromosome is duplicated (copied). Chromosomes Each chromosome consists of two identical “sister” chromatids. Sister chromatids Each pair of chromatids is attached at an area called the centromere. Centromere Copyright Pearson Prentice Hall Chromosomes When the cell divides, the chromatids separate. Each new cell gets one chromatid – which becomes a new chromosome for the new cell Draw and label a chromosome: Draw and label a chromosome: The “other” Sister Chromatid Sister Chromatid centromere the whole thing is a chromosome chromatin DNA • When can you see chromosomes? Normally the DNA is unraveled as Chromatin …. BUT During Mitosis you can see the DNA as chromosomes!!! Mitosis Is divided into four phases: Prophase Metaphase Anaphase Telophase (PMAT) Bellwork: Fri. Oct. 23, 2015 1. Draw the dividing plant and animal cells and label the dividing features J Plant: forms a “cell plate” Animal: forms a “cleavage furrow” What is this? Copyright Pearson Prentice Hall cleavage 1 Interphase 2 Prophase Nuclear DNA = chromatin membrane Sister chromatids 3 Metaphase centrioles centromere Spindle fiber 5 Telophase 4 Anaphase Slide 17 of 38 End Show 1 Interphase 2 Prophase Nuclear DNA = chromatin membrane Sister chromatids 3 Metaphase centrioles centromere Spindle fiber 5 Telophase 4 Anaphase Slide 18 of 38 End Show Cytokinesis in an animal cell Cytokinesis in Plants In plants, a structure known as the cell plate forms midway between the divided nuclei. Cell plate Cell wall Copyright Pearson Prentice Hall http://www.biologycorner.com/bio1/cellcycle.html Animals - cell pinches inward Plants - a new cell wall forms between the two new cells Bellwork: Mon. Oct. 26, 2015 Do you know the 4 phases of mitosis? Prophase Metaphase _________ __________ _________ Telophase Anaphase _______ What is the long phase between mitosis? Interphase ___________ Series of events cells go through as they grow and divide. Interphase: period of growth that occurs between cell divisions. During cell cycle: cell prepares for division grows divides to form 2 daughter cells - each of which begins the cycle again Cell Cycle = 4 phases – 1st 3 occur during Interphase: G1 (First Gap Phase) S Phase G2 (Second Gap Phase) M Phase (mitosis) use your ruler to divide one quarter into fifths Now label the G1 Phase Phases of the S Phase Cell Cycle G1, S, G2 are Interphase!!! Mitosis G2 Phase PMAT !!! Cell Cycle Cell increases in size & synthesizes new proteins and organelles chromosomes are replicated DNA synthesis takes place Organelles & molecules required for cell division made Cell Cycle Cell increases in size & synthesizes new proteins and organelles chromosomes are replicated DNA synthesis takes place Organelles & molecules required for cell division made Why Do Cells Divide? •Reproduction •Growth •Repair Mitosis: nuclear division, number of chromosomes remains the same Skin cells are always “falling off” of us so skin is constantly going through mitosis to replace the lost skin cells Mitosis – Cell Cycle • http://www.youtube.com/watch?v=C6hn3sA0ip0 What's the difference between identical and fraternal twins? • http://www.youtube.com/watch?v=LSJKXl K3Lx8 Cell getting ready to come out of Interphase and move into early prophase During telophase the cell looks like a “telophone” You can see the “cleavage furrow” right before cytokinesis in later telophase Chromosomes condensing in later prophase Chromosomes “met” up in the middle during metaphase Sister chromatids being “ripped apart” during anaphase But when you look at a cell it may not be so clearly defined Mitosis Section 10-2 Spindle forming Prophase Prophase Chromosomes (paired chromatids) Centromere Click to Continue Copyright Pearson Prentice Hall Mitosis Spindle forming Prophase Prophase is the first and longest phase of mitosis. The centrioles separate and take up positions on opposite sides of the nucleus. Centromere Chromosomes (paired chromatids) Copyright Pearson Prentice Hall Mitosis The centrioles lie in a region called the centrosome. The centrosome helps to organize the spindle, a fanlike microtubule structure that helps separate the chromosomes. Spindle forming Centromere Chromosomes (paired chromatids) Copyright Pearson Prentice Hall Mitosis Spindle forming Chromatin condenses into chromosomes. The centrioles separate and a spindle begins to form. The nuclear envelope breaks down. Centromere Chromosomes (paired chromatids) 10-2 Cell Division Slide 43 of 38 End Show Mitosis Metaphase Centriole Spindle Centriole Metaphase Click to Continue Copyright Pearson Prentice Hall Mitosis Centriole Metaphase The second phase of mitosis is metaphase. The chromosomes line up across the center of the cell. Microtubules connect the centromere of each chromosome to the poles of the spindle. Spindle Copyright Pearson Prentice Hall 10-2 Cell Division Slide 46 of 38 End Show Mitosis Anaphase Individual chromosomes Anaphase Copyright Pearson Prentice Hall Mitosis Anaphase Individual chromosomes Anaphase is the third phase of mitosis. The sister chromatids separate into individual chromosomes. The chromosomes continue to move until they have separated into two groups. Copyright Pearson Prentice Hall 10-2 Cell Division Slide 49 of 38 End Show Mitosis Telophase Nuclear envelope reforming Telophase Copyright Pearson Prentice Hall Mitosis Telophase Telophase is the fourth and final phase of mitosis. Chromosomes gather at opposite ends of the cell and lose their distinct shape. Copyright Pearson Prentice Hall Mitosis A new nuclear envelope forms around each cluster of chromosomes. Copyright Pearson Prentice Hall 10-2 Cell Division Slide 53 of 38 End Show Cytokinesis Cytokinesis Cytokinesis Copyright Pearson Prentice Hall Cytokinesis During cytokinesis, the cytoplasm pinches in half. Each daughter cell has an identical set of duplicate chromosomes Bellwork: Thurs. Nov. 4, 2010 Series of events cells go through as they grow & divide is called a. cell cycle. b. mitosis. c. interphase. d. cytokinesis. Copyright Pearson Prentice Hall 10-2 Longest phase in mitosis is a. prophase. b. metaphase. c. anaphase. d. telophase. 10-2 Longest phase in cell cycle is a. interphase. b. cytokinesis c. prophase d. metaphase Copyright Pearson Prentice Hall DNA replication takes place during the a. S phase of the cell cycle. b. G1 phase of the cell cycle. c. G2 phase of the cell cycle. d. M phase of the cell cycle. Copyright Pearson Prentice Hall Bellwork: Thurs. Nov. 4, 2010 During mitosis, “sister” chromatids separate from one another during a. telophase. b. interphase. c. anaphase. d. metaphase. Copyright Pearson Prentice Hall