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Biotech students wbat recall the steps of the Central Dogma while watching The DNA, The DNA and Central Dogma videos. You will define the central dogma vocabulary as a class. You will compare DNA and RNA as a pre- and post assessment individually. DNA DNA Replication The Central Dogma of Molecular Biology Replication DNA duplicates DNA RNA Transcription Information DNA RNA Protein Translation Information Transcription RNA synthesis RNA RNA polymerase Nucleus mRNA Nuclear membrane Cytoplasm ribosome mRNA Translation Protein synthesis Protein protein (Andy Vierstraete 1999) Why it happens How it happens Store and maintain the integrity of the information from cell to cell or parent to offspring. Takes place pre-mitosis and meiosis. Uses original (parent strand) as a template to create to new daughter strands (semi-conservative replication). Translation Transcription Why it happens How it happens DNA’s message (gene) is expressed (turned on) by first being transcribed into RNA (mRNA, tRNA or rRNA) mRNA=messenger RNA, carries DNA’s message to be later translated into proteins with the help of tRNA and the ribosome. Why it happens How it happens To make a protein (phenotype) the mRNA is translated with the help of the ribosome (rRNA) and tRNA (transfer RNA) which carries amino acids to the mRNARibosome complex. Shape Bases Double helix A,T,G,C Single helix A,U,G,C › U=a pyrimidine called Uracil Sugar Deoxyribose Ribose List 2 ways RNA is different from DNA. What comes first translation or transcription?