Download Central Dogma.pptx

 Biotech
students wbat recall the
steps of the Central Dogma while
watching The DNA, The DNA and
Central Dogma videos.
 You
will define the central dogma
vocabulary as a class.
 You will compare DNA and RNA
as a pre- and post assessment
individually.
DNA DNA
Replication
The Central Dogma of Molecular Biology
Replication
DNA duplicates
DNA  RNA
Transcription
Information
DNA
RNA  Protein
Translation
Information
Transcription
RNA synthesis
RNA
RNA polymerase
Nucleus
mRNA
Nuclear membrane
Cytoplasm
ribosome
mRNA
Translation
Protein synthesis
Protein
protein
(Andy Vierstraete 1999)
Why it happens
How it happens
 
 
 
Store and maintain the integrity of the
information from cell to cell or parent to
offspring.
Takes place pre-mitosis and meiosis.
Uses original (parent strand) as a
template to create to new daughter
strands (semi-conservative replication).
Translation
Transcription
Why it happens
How it happens
 
 
DNA’s message (gene) is expressed
(turned on) by first being transcribed into
RNA (mRNA, tRNA or rRNA)
mRNA=messenger RNA, carries DNA’s
message to be later translated into
proteins with the help of tRNA and the
ribosome.
Why it happens
How it happens
 
To make a protein (phenotype) the mRNA
is translated with the help of the ribosome
(rRNA) and tRNA (transfer RNA) which
carries amino acids to the mRNARibosome complex.
Shape
Bases
 
 
Double helix
A,T,G,C
 
 
Single helix
A,U,G,C
›  U=a pyrimidine
called Uracil
Sugar
 
Deoxyribose
 
Ribose
  List
2 ways RNA is different from DNA.
  What comes first translation or
transcription?