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Name: _____________________________________ Block: ______ How Does DNA Determine the Traits of an Organism? Introduction: In this simulation, you will examine the DNA sequence of a fictitious organism: the Snork. Snorks were discovered on the planet Dee Enae in a distant solar system. Snorks only have one chromosome with 6 genes on it. You job is to analyze the genes of its DNA and determine what traits the organism has. SNORK DNA AND TRAITS tRNA triplet Amino Acid Number ACC 20 Amino Acid Sequence Trait AGC 16 20-11-13 hairless CGA 2 20-12-13 hairy AAC 4 20-12-12 plump CGC 3 13-14-15 skinny GGG 5 16-2 - 5 4 legged AGG 7 16-5 - 2 2 legged AAA 8 12-7-8 round head UUU 9 5-7-8 block head GGU 12 9-8 - 8 no tail UAU 13 9-4 - 8 tail CCC 1 11-3-2 slanted eyes AUC 6 11-3-3 wide round eyes CUA 10 6-6-10 male GGA 11 6-6-14 female UAA 14 Observations and Analysis of Snork DNA You are given a chromosome from a Snork with the following sequence. Each gene has only 3 amino acids. Your job is to determine the sequence of amino acids for your specimen. Write the complimentary mRNA, tRNA, the amino acid sequence it codes for and the related trait in the chart below. Gene DNA mRNA tRNA Amino Acid Trait 1 ACCGGTTAT 2 AGCCGAGGG 3 TTTAACAAA 4 GGACGCCGA 5 GGGAGGAAA 6 ATCATCCTA Now, what would happen if there were mutations in the Snork’s DNA? Fill in the table below using the changes described: If the AAC codon on the 3rd gene underwent a Substitution mutation, and the new DNA strand read: TTTAAAAAA If the 1st gene underwent a Duplication mutation, and the new DNA strand read: ACCGGTGGT If the 6th gene underwent a Deletion mutation, and the new DNA strand read: ATCATCTAA If the 2nd gene underwent an Inversion mutation, and the new DNA strand read: AGCGGGCGA Gene DNA Mutation 1 ACCGGTTAT 2 AGCCGAGGG 3 TTTAACAAA 4 GGACGCCGA 5 GGGAGGAAA 6 ATCATCCTA mRNA tRNA Amino Acid Trait Now, draw your Snorks! BEFORE MUTATIONS Questions: 1. How are proteins affected by DNA mutations? AFTER MUTATIONS 2. What mechanisms are in place to try and prevent these mutations from occurring? 3. We often think of mutations being only bad things. Imagine that the mutations in the Snork’s DNA made it super attractive to other Snorks, and it ended up having many offspring and being very well adapted. Would this be a good or bad mutation? Why?