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BI102: GENERAL BIOLOGY
WINTER, 2007
MIDTERM #3B
Student Name:
1. Which of these sequences correctly describes the cell cycle?
A) G1 => G2 => S => prophase => metaphase => anaphase => telophase
B) S => G2 => prophase => metaphase => anaphase => telophase => G1
C) G1 => S => G2 => prophase => anaphase => metaphase => telophase
D) prophase => metaphase => telophase => anaphase => G1
=>
S => G2
E) G1 => S => G2 => metaphase => prophase => anaphase => telophase
Answer questions 2 through 5 by matching the term on the left with the definition on the right
2.
3.
4.
5.
centromere
chromatid
diploid cells
homologs
A. a single DNA molecule
B. chromosomes with the same genes, but may have different alleles
C. contain pairs of homologous chromosomes.
D. point of attachment of the replicated arms of a chromosome.
Using the following phases of the cell cycle as answers, pick the single most correct choice for each
of the statements numbered 6 through 9.
A. S B. G1
C. G2
D. Cytokinesis
E. All of these
6) Spindle proteins are made.
7) DNA synthesis occurs.
8) Most cell growth occurs.
9) chromosomes composed of two attached chromatids
Answer questions 10 through 13 by matching the following. Each choice may be used more than once.
A. Prophase
B. Metaphase
C. Telophase
D. Anaphase
E. Interphase
10) Chromosomes move to the equator
11) Chromosomes duplicate
12) Chromosomes shorten and thicken
13) Sister chromatids move to opposite poles
14) Homologous chromosomes pair up (synapsis) during
A) mitosis.
B) meiosis I.
C) meiosis II. D) mitosis and meiosis II. E) protein synthesis.
15) Centromeres split during
A) anaphase I and anaphase II of meiosis.
B) anaphase of mitosis and anaphase I of meiosis.
C) cytokinesis of mitosis and meiosis I
D) the S portion of interphase.
E) anaphase of mitosis and anaphase II of meiosis.
16) The chromosome number is reduced from diploid to haploid during
A) mitosis.
B) meiosis I.
C) meiosis II. D) interphase. E) S phase of mitosis.
17) Haploid cells
A) can result from meiosis.
B) cannot be produced by mitosis.
C) function as gametes or spores in sexually reproducing organisms.
D) have one member of each pair of homologous chromosomes.
E) Both choices A and C are correct.
18) If there are 12 chromosomes in a cell that has just completed meiosis II, what is the diploid
number of chromosomes for that organism?
A) 6
B) 12
C) 24 D) 24 pairs
E) either 6 or 24, depending on the cell type
19) Chromosomes of a homologous pair separate from each other during
A) anaphase I.
B) metaphase I.
C) prophase II
D) anaphase II
E) metaphase II.
20) Which of the following statements is FALSE?
A) Meiosis separates homologous chromosomes in a diploid cell to produce haploid daughter
cells containing one copy of each type of chromosome.
B) During prophase I, homologous chromosomes pair up and exchange DNA.
C) During meiosis II, paired homologous chromosomes
move up to the equator of the cell.
D) During anaphase I, homologous chromosomes
separate.
E) In meiosis II, the sister chromatids of each
chromosome separate.
Answer questions 21 through 25 by matching the
following term to its number in either of these two
diagrams. Each choice may be used more than once or
not at all.
A. DNA
B. mRNA
C. translation
D. transcription
E. protein
Answer questions 26 through 28 by matching the
following term to its number in either of these two
diagrams. Each choice may be used more than once or
not at all.
A. anticodon
B. peptide bond formation
C. codon
D. tRNA
E. mRNA
29) Which is NOT found in DNA?
A) adenine
B) deoxyribose sugar
C) phosphate group
D) phospholipid group
E) thymine
30) In Griffith's experiments, what happened when heat-killed S-strain pneumococcus were injected
into a mouse along with live R-strain pneumococcus?
A) DNA from the live R-strain was taken up by the heat-killed S-strain, converting them to R-strain
and killing the mouse.
B) DNA from the heat-killed S-strain was taken up by the live R-strain, converting them to S-strain
and killing the mouse.
C) Proteins released from the heat-killed S-strain killed the mouse.
D) RNA from the heat-killed S-strain was translated into proteins that killed the mouse.
E) nothing
31) The correct structure of a nucleotide is
A) phosphate-5 carbon sugar-nitrogen base.
B) phospholipid-sugar-base.
C) phosphate-sugar-phosphate-sugar.
D) adenine-thymine and guanine-cytosine.
E) base-phosphate-glucose.
32) The two polynucleotide chains in a DNA molecule are attracted to each other by
A) covalent bonds between carbon atoms.
B) covalent bonds between phosphates & sugars.
C). hydrogen bonds between bases
D) ionic bonds between "R" groups in amino acids
E). peptide bonds between amino acids.
33) The DNA of a certain organism has guanine as 30% of its bases. What percentage of its bases
would be adenine?
A) 0%
B) 10%
C) 20%
D) 30%
E) 40%
34) In the comparison of a DNA molecule to a twisted ladder, the uprights of the ladder represent
A) hydrogen bonds between bases.
B) deoxyribose linked to phosphates.
C) deoxyribose linked to sulfates.
D) nitrogenous bases linked to phosphates.
E) nitrogenous bases linked together.
35) The sequence of subunits in the DNA "backbone" is
A) --base--phosphate--base--phosphate--base--phosphate-.
B) --phosphate--sugar--phosphate--sugar--phosphate--sugar.
C) --sugar--base--sugar--base--sugar--base--sugar--base-.
D) --base--sugar--phosphate--base--sugar--phosphate-.
E) --base--phosphate--sugar--base--phosphate--sugar-.
36) How does the Watson and Crick model of DNA structure help explain DNA replication?
A) Deoxyribose sugar always bonds to a nitrogenous base.
B) Four types of bases are found in DNA.
C) Phosphate groups always bond to deoxyribose sugar.
D) Precise base pairing allows the base sequence to be copied.
E) The number of purines equals the number of pyrimidines.
37) Which of the following is TRUE about the accuracy of DNA replication?
A) Many errors are made during DNA replication, but this does not matter because repair
enzymes will mend the errors.
B) Many errors are made during DNA replication, but this does not matter because of the
immense size of the DNA molecule.
C) The few errors made by DNA polymerase are usually corrected by repair enzymes.
D) DNA polymerase makes very few errors, so no repair enzymes are needed.
E) DNA polymerase always makes a perfect copy of the original DNA.
Answer questions 38 through 40 by matching the
following term to its number in the diagrams. Each
choice may be used more than once or not at all.
A. 3’ end
B. origin of replication
C. helicase
D. 5’ end
E. makes sure that complementary base pairing
occurs
41) According to the Law of Segregation, in an
organism with the genotype Aa
A) all the gametes will have gene a.
B) half the gametes will have A and half will
have a
C). all the gametes will have gene A
D) 3/4 of the gametes will have A and 1/4 will
have a.
E) 1/4 of the gametes will have A and 3/4 will
have a.
42) When genes are linked, the reason a few of the recombinant genotypes still occur in the
offspring is because of
A) crossing over.
B) linkage.
C). mutation
D) natural selection.
E) independent assortment.
43) Which of the following statements is FALSE?
A) Individuals with the same genotype might have different phenotypes.
B) Matings between individuals with dominant phenotypes cannot produce offspring with recessive
phenotypes.
C) Matings between individuals with recessive phenotypes usually do not produce offspring with
dominant phenotypes.
D) Individuals with the same phenotype might have different genotypes.
E) All of the above choices are correct.
Answer questions 44 through 47 by matching the following. Each choice may be used more than once
A. Genotype
B. Incomplete dominance
C. Heterozygote
D. Homozygote
E. Phenotype
44) An individual having 2 identical alleles at a particular locus.
46) The entire genetic constitution of an individual.
45) The Bb individual.
47) The appearance of a Bb individual.
48) The failure of chromosomes to segregate properly during meiosis is called
A) nondisjunction.
B) translocation.
C) replication.
E) independent assortment.
D) inversion.
Answer numbers 49 and 50 by filling in selection “A” on your answer sheet if the answer is true an “B”
if the statement is false
49) Females who receive sex-linked genes always express them.
50) Only males can express sex-linked traits.
51. Diagram a cross between heterozygotes for both the “B” and the “E” genes if the e gene is sex
linked
Only answers within the boxes will be graded
Genotypic ratio:
Phenotypic ratio:
52. Determine the genotype and phenotype of the parents that produced a litter with equal numbers
of yellow and chocolate puppies
The boxes below are provided for your assistance –
you don’t have to use them if you don’t need to in order to answer the question.
Genotypic ratio:
Phenotypic ratio: