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Name__________________________ Date______ Period_______ Protein Synthesis 1. The production of proteins is called _____________ _____________. 2. Proteins are made of chains of ___________ __________ held together by ___________ bonds. 3. How many amino acids are there? 5. Each combination of three nucleotides on mRNA is called a _____________ and codes for a specific __________ __________. 7. Do some amino acids have more than one codon? Give an example. 8. Name the start codon. 9. Name the 3 stop codons. 10. Define translation. 11. Where does translation occur in a cell? 12. The cell organelle known as the ___________ is where proteins are made. 13. Amino acids are carried to the ribosome by ___________. 14. Transfer RNA (tRNA) has a sequence of three nucleotides called the _____________ that binds to the ________ of mRNA. 16. A tRNA with an anticodon of UGA would pair with what mRNA codon? What amino acid would this codon code for? 17. Ribosomes are composed of ___________ and _________ and may be attached to the _______________ _____________ or be free in the ______________. 20. One site holds the __________ transcript, while the other sites hold __________ with their attached amino acid. 23. Amino acids are attached to each other with __________ bonds as the ribosome moves down the mRNA strand. 24. The ribosome moves down the mRNA _________ nucleotides at a time. 29. Complete the following table: DNA triplet mRNA codon tRNA anticodon Amino Acid TAG UAG CCA AUC AUG RNA 2. In eukaryotes, the genes (instructions for making proteins) are located in the ___________, while the amino acids to make proteins are found in the ______________. 3. _________ is the nucleic acid that copies DNA’s instructions in the nucleus & takes them to the cytoplasm. 4. What does RNA stand for? 5. What is the sugar on RNA? 6. RNA does not contain the base ___________, instead it contains the base ___________. 7. DNA is double stranded, while RNA is ___________ stranded. 8. Name the 3 types of RNA and give their abbreviations. a. b. c. 9. ____________ RNA actually copies DNA’s instructions in the nucleus & then moves to the ___________. 13. Where does transcription take place? 20. If this is the sequence on the DNA template strand (AATCGGCTAAGC), what RNA nucleotides would be added? 1 24. After transcription, the newly made _________ moves through the __________ of the nuclear membrane out into the cytoplasm. Name the parts/structures of a cell: A = __________________ B = __________________ C = __________________ D = __________________ E = __________________ F = __________________ Use words from the word bank to match the following: messenger-RNA ___________________ ___________________ ___________________ ___________________ ___________________ ___________________ ___________________ transfer-RNA ribosomal-RNA Carries the DNA code from nucleus to cytoplasm Made by the nucleolus Adds the correct amino acid to the growing protein chain Combines with proteins to form ribosomes Has a CODON region Has an ANTICODON region ___________________ __________________ If the given diagram represents a part of the process of protein synthesis, strand A would… a. b. c. d. Serve as a template for the synthesis of messenger RNA Carry a code determined by the original DNA molecule from the nucleus to the cytoplasm Pick up and transfer specific amino acids to the cytoplasm Pick up and transfer nucleic acids to the nucleus The messenger RNA codes for six different amino acids are shown in the table below. MESSENGER RNA CODONS FOR AMINO ACIDS Amino Acid Messenger RNA Codons Arginine CGU, CGC, CGA, CGG Cysteine UGU, UGC Glutamic acid GAA, GAG Leucine CUU, CUC, CUA, CUG Serine AGU, AGC Valine GUU, GUC, GUA, GUG 1. In one type of mutated gene for hemoglobin, CAC has replaced the normal CTC in the DNA code. What amino acid substitution has taken place in the mutated hemoglobin? 2