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Name: ________________________________________ Period: _____ Date: _____________________ DNA Workshop: “Make Yourself” Some Proteins Directions: Answer the following questions based on the reading and computer simulation of DNA & Protein Synthesis from the PBS DNA Workshop Activity. To access the site, go to sillsscience.com, click Biology Projects and Web Activities, scroll down and click the link DNA Workshop and Protein Synthesis. Please follow the continued directions in bold. 1. In what year was the DNA molecule first presented? ___________________________ Please click on “DNA Replication” and answer the following questions. 2. What are the 3 parts to a nucleotide? _______________________________ 3. Name the 4 nitrogen bases in DNA: ________________________________ 4. Name the complementary base pairs for Adenine and Guanine. ____________________ 5. Briefly describe the process of DNA replication. ___________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 6. Why does DNA replication occur? _________________________________________________ Please return to the original screen and click on “DNA Workshop Activity”. On the left of your screen click on “DNA Replication”. Click on “unzip the cell”. 7. Where does DNA replication occur? ___________________________________________ 8. What is the first step in DNA replication? (Hint: What did the DNA do after you clicked unzip?). ___________________________________________________________. Click “ok”. Using your mouse, move the appropriate nitrogen bases next to their complement on the DNA molecule. 9. Draw the 2 strands of DNA after you have matched up the complementary base pairs. Return to the original screen and click on “Protein Synthesis” 10. 11. 12. 13. What is the function of DNA? ___________________________________________________ The_________that make up DNA control the life of the entire organism. What are the building blocks of a polypeptide or protein? _________________________. How many seconds does it take to create a protein chain that is 400 _______________________________ amino acids long? Return to the original screen and click on “DNA Workshop Activity”. Click on the words “ Protein Synthesis” on the right of your screen. 14. Where does the first step of protein synthesis (the unzipping of the DNA) occur in the cell? ____________________________. Click on “Unzip” 15. What occurred when the DNA unzipped? ________________________________________. Click “ok” and match the mRNA nucleotides with their complementary base pairs on the DNA by moving the bases with your mouse over to the DNA. 16. Which nucleotide is found only in RNA? _________________________________________. 17. What is the complementary base pair for this nucleotide? ___________________________. 18. What is the name of the process in which the message of DNA is transcribed into the message of RNA? ____________________________________________________________. 19. What is the formal name for mRNA? __________________________________ 20. Draw the DNA with the mRNA attached. 21. Where does the mRNA go after it has transcribed the DNA code? ____________________ Click “ok”. tRNA or Transfer RNA has an anticodon (3 bases) and an amino acid that it is specific to. 22. What is the name of the second step in protein synthesis? ________________________ Match the anticodons of the tRNA, by using your mouse, with the codons of the mRNA on the ribosome. 23. What process occurs at the ribosomes? ___________________________________. 24. What is the name of the first amino acid created? ______________________________. Click “ok” and match the second anticodon with its codon. 25. What happens to the tRNA after it deposits its amino acid? _________________________. Click “ok” and match the third anticodon with its codon. 26. Diagram the mRNA attached to a ribosome. Next draw the correct tRNA’s attached to the codons of its corresponding mRNA. 27. List the 3 amino acids in order for your polypeptide chain. _________________________. 28. What do you hypothesize will happen to the mRNA nitrogen bases after translation is completed? ____________________________________________________________________________________________________ ____________________________________________________________________________________________________ 29. Describe the steps involved in translation. ___________________________________________________________ ____________________________________________________________________________________________________ ____________________________________________________________________________________________________ ____________________________________________________________________________________________________ ____________________________________________________________________________________________________