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Core – Practice test 4 Genetics Remember what an inference is? • An explanation based on observations Sexual VS Asexual Reproduction • • • • • • • • Sexual – two parents Meisois Testies and ovaries Fusion of egg and sperm to form a zygote seeds, flowers Increase variation Evolution Changing environments • • • • • • Asexual – one parent Mitosis Somatic, body cells Cloning Exact copy No variation (unless mutation) • Produce many offspring A normal human cell has 46 chromosomes. After a cell undergoes meiosis, how many chromosomes will the resulting cells have? • 23 • In which organ of an animal's body would meiosis occur? • Testis and ovaries • In a plant? • flower In changing environments, is asexual or sexual better? • Sexual. Why? • The increase in genetic variability. • Why would some grasses be able to grow on ground polluted by an oil spill • Genetic variation within the grass species allows some to survive and reproduce. What do you know about the Irish Potato Famine? • 1845 A fungus like protist destroyed the Irish potato crop which was the main source of food for one third of the population. This led to a 7 year famine. Why did one little fungus cause so much trouble? • Potatoes grow by asexual reproduction therefore the potatoes lack variations that could have withstood the infection. When environmental conditions are bad or change, is sexual or asexual reproduction better? • Sexual reproduction • Why? • It increases genetic variation (like having more choices). How does asexual reproduction help the survival of a species • Asexual reproduction may result in many offspring with the same strong useful characteristics as the parent. Forms of Asexual Reproduction • • • • • • • • Mushroom reproduce by producing– spores Bacteria reproduce by– fission Hydra – budding Tulips (and things with bulbs) – vegetative Reproduction/Plants • Is it better to reproduce with spores or seeds? • Seeds • Why? • Seeds contain stored nutrients for nourishment and a hard protective coat. Chromosome number • In sexual reproduction (meiosis) what happens to the chromosome number? • It is cut in half (humans 46 to 23) • In Asexual reproduction – chromosome number? • Stays the same. From DNA to Protein DNA vs. RNA • • • • • • • • • DNA (where?) Nucleus only How many strands? Double stranded What type of sugar? De oxy ribose Bases are . . . . . A-T and G-C • RNA (where) • mRNA from nucleus to cytoplasm • tRNA and rRNA – cytoplasm • How many strands? • Single stranded • What type of sugar? • Ribose • Bases? • A-U • G-C What does DNA look like? • A twisted latter. How were discoveries of DNA made? • A lot of people involved. • Watson, Crick, Wilkins, Franklin and more • What did they do? • They did many experiments and Watson and Crick made a model. Central Dogma • • • • • • What is Replication? DNA to DNA Where? Nucleus What is Transcription? DNA to mRNA • • • • • • Where (transcrition) Nucleus What is Translation? RNA to Protein Where? Cytoplasm on the Ribosome DNA to Protein How does DNA get from the nucleus to the ribosomes? • It jumps • Just kidding – mRNA (messanger RNA) takes the message from the nucleus to the ribosomes. Patterns of inheritance 1. Which trait usually shows dominant or recessive? 2. dominant 3. Wavy hair is where both are dominant or _________ dominance. 4. codominance 5. If I cross a white and red flower and get pink. What is this? 6. Incomplete dominance inheritance • Eye color, hair color, height is what type of inheritance? • Polygenic • Blood type is what type of inheritance? • Multiple allelic and codominance Words to know • • • • • • Hetero zygote Different - Rr Homo zygote dominant Same - RR Homo zygote recessive Same - rr • • • • Gene o type Genes RR, RR, rr Pheno type Physical stuff – red, white, tall, short Punnet Squares • If you cross a Green pea with a yellow pea and get all green peas, why is this? • Green is dominant over yellow. • Then, if I cross these kids, what will happen? G G g Gg Gg g Gg Gg G g G GG Gg g Gg gg – some yellow will show up Genetic Technologies • And genetic engineering. Selective breeding is also called what? • Artificial Selection. • Why? • Humans select for certain traits instead of nature (as in natural selection) • An orchard in California makes really great oranges. They want to maintain this high quality. How should they do this? • Clone the trees – Take cuttings from the already fabulous trees and make trees. What is the process called when an egg is removed, fertilized outside of the body, and then implanted in the womb? • in vitro fertilization Selective breeding • Also called • Artificial selection • Breeder/farmer chooses only the best animals or crops • Examples • Corn Hybrid • Race horses • Shetland pony • Siamese cat Genetic technologies • How do we do genetic testing on fetus? • Amniotic fluid can be taken to diagnose prior to birth (and possibly fix) DNA profiling (CSI) • • • • • • Also called? DNA fingerprinting and Gel electrophoresis Used for? Identify the killer Who’s the dad? Gene Therapy • • • • Also called? Recombinant DNA? What is it? Insert a foreign gene into a host • Being used for • (cystic fibrosis) • Use bacterial plasmids to make? • Insulin • Human Growth Hormone (HGH) • Interferon • Other stuff. Other Genetic technologies • Cloning • Increase food supply, improve health, better medicines, transplants etc. • Stem cell research On the board • Punnet squares and pedigrees.