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CELLS AND THEIR FUNCTIONS “I CAN’T IMAGINE A PERSON BECOMING A SUCCESS WHO DOESN’T GIVE THIS GAME OF LIFE EVERYTHING HE’S GOT.” WALTER KRONKITE PLASMA MEMBRANE NUCLEUS CYTOPLASM SURFACE ORGANELLES CELLULAR DIVERSITY CELL STRUCTURE – SEE TABLE 3-1 PAGE 38 MEMMLER NUCLEIC ACIDS – DNA, RNA DNA – CHROMOSOMES IN THE NUCLEUS ◦ ◦ ◦ ◦ ◦ ADENINE (A) THYMINE (T) GUANINE (G) CYTOSINE (C) DOUBLE HELIX W/ H+ BONDS RNA – IN CYTOPLASM (Mrna, Rrna, Trna) ◦ ADENINE, GUANINE, CYTOSINE ◦ THYMINE IS REPLACED BY URACIL (U) ◦ SINGLE STRAND PROTEIN SYNTHESIS EVERYBODY UP!!!! WE ARE GOING TO BUILD A STRAND OF PROTEIN Build a protein strand MITOSIS VS MEIOSIS INTERPHASE PROPHASE METAPHASE ANAPHASE TELEPHASE ROLE OF THE CENTROMERES CELL DIVISION PASSIVE MOVEMENT ◦ ◦ ◦ ◦ SIMPLE DIFFUSION OSMOSIS FILTRATION FACILITATED DIFFUSION ACTIVE TRANSPORT ◦ ◦ ◦ ◦ NEED PROTEIN ‘GATE KEEPERS’ SELECTIVE PERMEABILITY ENDOCYTOSIS – PHAGOCYTOSIS & PINOCYTOSIS EXOCYTOSIS MOVEMENT OF SUBSTANCES SEE TABLE 3-4 PAGE 49 ISOTONIC – SAME SOLUTE CONCENTRATION AS OUR BODY (0.9% NS) HYPOTONIC – LESS SOLUTE IN SOLUTION THAN OUR BODY; FREES UP WATER TO GO TO CELL; TOO MUCH = HEMOLYSIS (0.45% NaCl) HYPERTONIC – MORE SOLUTE THAN OUR BODY; PULLS WATER TOWARD IT; TOO MUCH DEHYDRATED CELL = CRENATION (3% NaCl) TONICITY Golgi apparatus – the “UPS” of the cell; packages the items for transport in and out of the cell Mitochondria – the “Mighty” power house that makes energy (ATP) from the glucose Lysomes – clean up the cell waste (garbage men); think Lysol Centrioles – necessary for reproduction Peroxisomes – Clean up hazardous material (HAZ MAT team) ORGANELLES Smooth endoplasmic reticulum – makes and packages fats Rough endoplasmic reticulum – makes proteins Ribosomes – make proteins Vacuoles – empty cargo containers Vesicles – carrier of solutes within the cell; could be storage or for movement to cell side for exocytosis ORGANELLES – CONT’D LIMITED NUMBER OF CELL DIVISIONS MUTATIONS CAN OCCUR DURING DIVISION THESE MUTATIONS MAY CAUSE A CELL TO DIVIDE FOREVER RISK FACTORS: HEREDITY (BRACA1) , CHEMICAL EXPOSURE, IONIZING RADIATION (XRAYS, SUN), PHYSICAL IRRITATION, DIET, VIRUSES (HPV) CELL AGING AND CANCER RISKS CYT/OMICR/OBI-SOME, SOM/ACHROM/OEND/OLYS/OINTER- MEDICAL TERMINOLOGY CYT/O MICR/O BI -SOME, SOM/A CHROM/O END/O LYS/O INTER PRO META ANA TEL/E SEMI PHAG/O PIN/O EX/O ISO HYPO HYPER CARCIN/O -GEN MEDICAL TERMINOLOGY