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A TOUR OF THE CELL A TOUR OF THE CELL • MICROSCOPES PROVIDE WINDOWS TO THE WORLD OF THE CELL – THERE ARE MANY DIFFERENT TYPES OF MICROSCOPES • COMPOUND LIGHT MICROSCOPE A TOUR OF THE CELL A TOUR OF THE CELL • COMPOUND LIGHT MICROSCOPE • PHASE CONTRAST MICROSCOPE • ELECTRON MICROSCOPE – SCANNING VS. TRANSMISSION A TOUR OF THE CELL • RESOLUTION VS MAGNIFICATION A TOUR OF THE CELL • FIELD OF VIEW – MICRONS (MICROMETERS) – LOW POWER F.O.V. VS HIGH POWER F.O.V A TOUR OF THE CELL • CELL SIZE VARIES WITH FUNCTION – CHICKEN EGG VS HUMAN EGG – WHAT’S THE LONGEST CELL AROUND? A TOUR OF THE CELL • NATURAL LAWS LIMIT CELL SIZE – WHAT’S THE MINIMUM SIZE FOR A CELL? – WHAT’S THE MAXIMUM SIZE FOR A CELL? • THE SURFACE AREA TO VOLUME RATIO DILEMMA A TOUR OF THE CELL • PROKARYOTIC CELLS – DEFINITION?? A TOUR OF THE CELL • PROKARYOTIC CELL ORGANELLES – NUCLEOID – RIBOSOMES – PLASMA MEMBRANE – CELL WALL – CAPSULE – PILI – FLAGELLUM A TOUR OF THE CELL • EUKARYOTIC CELLS – DEFINITION?? A TOUR OF THE CELL • WHAT IS THE ADVANTAGE TO HAVING MEMBRANE BOUND ORGANELLES? • CYTOPLASM? • ORGANELLES? • MOST ORGANELLES OVERLAP/EXIST IN BOTH PLANT AND ANIMAL CELLS – EXCEPTIONS?? • CHLOROPLASTS, CELL WALLS, LYSOSOMES, CENTRIOLES A TOUR OF THE CELL • HOW ARE WE GOING TO SORT THROUGH ALL OF THESE ORGANELLES? – ONE AT A TIME!!! A TOUR OF THE CELL • THE NUCLEUS – THE GENETIC CONTROL CENTER OF THE CELL A TOUR OF THE CELL • THE NUCLEUS – THE GENETIC CONTROL CENTER • • • • • DNA?? CHROMATIN?? CHROMOSOMES?? NUCLEAR ENVELOPE?? NUCLEOLUS?? A TOUR OF THE CELL • THE ENDOMEMBRANE SYSTEM – NETWORK OF ORGANELLES THAT WORK TOGETHER IN THE SYNTHESIS, STORAGE, AND EXPORT OF IMPORTANT MOLECULES A TOUR OF THE CELL • ROUGH ENDOPLASMIC RETICULUM – ROUGH E.R. – NETWORK OF INTERCONNECTED FLATTENED SACS, COVERED WITH RIBOSOMES, WITH TWO MAIN FUNCTIONS • MAKE MORE MEMBRANE • MAKE PROTEINS TO BE SECRETED BY THE CELL A TOUR OF THE CELL • ROUGH E.R. A TOUR OF THE CELL • SMOOTH ENDOPLASMIC RETICULUM – SMOOTH E.R. – CONTINUOUS WITH ROUGH E.R. BUT LACKS RIBOSOMES – FUNCTIONS • SYNTHESIS OF LIPIDS • STORAGE OF CALCIUM IONS (NEEDED FOR MUSCLE CONTRACTION) • SMOOTH E.R. IN THE LIVER – CONTROLS THE AMOUNT OF SUGAR – BREAKDOWN/DETOXIFIES DRUGS AND OTHER HARMFUL SUBSTANCES » YOU CAN GROW MORE SMOOTH E.R.?? » THIS EXPLAINS DEVELOPMENT OF TOLERANCE!!! A TOUR OF THE CELL • GOLGI APPARATUS (COMPLEX/BODY) – SERIES OF FLATTENED SACS – NOT INTERCONNECTED A TOUR OF THE CELL • GOLGI APPARATUS – ACTS AS “SHIPPING WAREHOUSE” – CHEMICALLY MODIFIES PROTEINS PRODUCED BY E.R., THEN SENDS THEM TO THEIR SPECIFIC DESTINATIONS A TOUR OF THE CELL • LYSOSOMES – “BREAKDOWN BODY”, CONTAINS HYDROLYTIC ENZYMES A TOUR OF THE CELL • LYSOSOMES – DIGEST TINY FOOD PARTICLES, BACTERIA, BUSTED ORGANELLES (HELPS RECYCLE PARTS) – ENZYMES MUST BE KEPT INSIDE MEMBRANE, OR ELSE!!!! A TOUR OF THE CELL • ENZYMES MUST BE KEPT INSIDE MEMBRANE, OR ELSE!!!! – ABNORMAL LYSOSOMES CAN CAUSE • LYSOSOMAL STORAGE DISEASES • POMPE’S DISEASE • TAY-SACH’S DISEASE Harrison Ford and Brendan Fraser star in "Extraordinary Measures." A TOUR OF THE CELL A TOUR OF THE CELL • VACUOLES – MEMBRANOUS SACS THAT HAVE VARIOUS FUNCTIONS (SHAPES AND SIZES) • CENTRAL VACUOLE • FOOD VACUOLE • CONTRACTILE VACUOLE A TOUR OF THE CELL • THE ENDOMEMBRANE SYSTEM A TOUR OF THE CELL • CHLOROPLASTS – PHOTOSYNTHESIZING ORGANELLES THAT CONVERT LIGHT ENERGY TO CHEMCIAL ENERGY A TOUR OF THE CELL • MITOCHONDRIA – CONVERT CHEMICAL ENERGY (SUGAR) INTO USEABLE ENERGY (ATP) A TOUR OF THE CELL • CYTOSKELETON – A SUPPORTIVE STRUCTURE OF FINE FIBERS • THREE MAJOR TYPES OF FIBERS – MICROFILAMENTS – MICROTUBULES – INTERMEDIATE FILAMENTS A TOUR OF THE CELL A TOUR OF THE CELL • CILIA AND FLAGELLA A TOUR OF THE CELL • CILIA AND FLAGELLA – BASAL BODIES – DYNEIN ARMS A TOUR OF THE CELL • CELL JUNCTIONS – DEFINITION?? – 3 MAJOR TYPES IN ANIMAL CELLS • ANCHORING • TIGHT • GAP (COMMUNICATING) – 1 TYPE IN PLANT CELLS • PLASMODESMATA A TOUR OF THE CELL • PLASMODESMATA A TOUR OF THE CELL • EXTRACELLULAR MATRIX – STICKY LAYER OF GLYCOPROTEINS IN WHICH CELLS ARE EMBEDDED A TOUR OF THE CELL FOUR MAJOR FUNCTIONAL CATEGORIES FOR EUKARYTOIC CELLS MANUFACTURE ENERGY PROCESSING BREAKDOWN PEROXISOMES SUPPORT/MOVEMENT/ COMMUNICATION A TOUR OF THE CELL • THE CELL MEMBRANE!!! A TOUR OF THE CELL • THE CELL MEMBRANE ONLY STARTS A NEW CHAPTER IN OUR LEARNING!!!