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The Cell Membrane 0 His friends call him the plasma membrane 0 He is thin and flexible 0 He has two main functions: 0 Protection – protects the cell from the outside environment 0 Regulation – controls what can enter and exit the cell 0 He is selective: allows some things to pass through more easily than others 0 He is selectively permeable: permeate is a fancy way to say “pass through.” What is the Fluid-Mosaic Model? 0 What’s a mosaic? 0 What does it mean to be fluid? 0 The cell membrane is NOT a rigid structure with immovable components! 0 The cell membrane is fluid-like and flexible 0 Within the membrane, molecules can move around What Is the Cell Membrane Made of? The (Phospho-)Lipid Bilayer 0 LIPIDS: Phospholipids make up the majority of the cell membrane Hydrophilic heads (polar) are made of phosphates (Phospho) Hydrophobic tails (nonpolar) made out of fatty acids (Lipid) 0 To protect the hydroPHOBIC tails from water, they form a bilayer which keeps the tails inside and the water- loving heads outside. More Parts of the Cell Membrane 0 Also embedded in the lipid bilayer are proteins and carbohydrate chains 0 Protein molecules bring materials into the cell and receive signals from outside the cell 0 Carbohydrate molecules (attached to proteins or lipids) have antenna to help cells identify or recognize other cells YouTube: Membrane Draw the Cell Membrane! Your turn! 0 Use your notes and what you’ve learned so far to complete the matching exercise in your notes 0 Protein (only) = B 0 Carbohydrate (only) = D 0 Lipid Bilayer = A 0 Phosphate Head = F 0 Fatty Acid Tail = G 0 Involved in Cell Recognition = D 0 Carbohydrate attached to a lipid = E 0 Helps move large material across the membrane = B 0 Carbohydrate attached to a protein = C 0 Outside cell = H Solutions 0 Molecules dissolved in a liquid = SOLUTES 0 Liquid/fluid dissolving them = SOLVENT 0 This makes a SOLUTION SALT is the solute and 0 In a salt solution, ______________ WATER is the solvent _____________ 0 In a sugar solution, sugar is the solute and water is the solvent. Dots = solute Space = solvent Concentration and Equilibrium 0 Solutions will spread out their dissolved molecules until they are equal throughout. 0 EQUILIBRIUM = molecules are spread equally 0 CONCENTRATION = # of molecules in an area per unit volume. High concentration: more solutes per unit volume Low concentration: less solutes per unit volume What happens with a barrier? (like a cell membrane) 0 If solutions on either side of the barrier have the same concentration, they are at equilibrium. 0 At equilibrium, both the solvent and solute move back and forth across the barrier: there is always movement. Transport of Materials Across the Cell Barrier 0 Materials move across the plasma membrane in two ways: 0 Passive Transport – movement across the membrane without using energy 0 Active Transport – movement across membrane that requires energy Types of Passive Transport: 1. Diffusion 0 Solutes move across a membrane from areas of high concentration (crowded) to low concentration 0 Diffusion = random particle movements, so does not use energy. Imagine warm air coming through an open window… Types of Passive Transport: 2. Osmosis 0 A special name for diffusion of water! 0 Water molecules (fast and small) pass through the cell’s selectively permeable membrane 0 Solute molecules are too large to pass -- only the water diffuses until equilibrium is reached. Types of Passive Transport: 3. Facilitated Diffusion 0 Large molecules or those with a charge need the help of a protein to pass across a cell membrane 0 Proteins form a channel and molecules move through the “doorway.” Each channel is specific to a particular type of molecule Doesn’t require energy => passive transport Active Transport 0 Movement AGAINST the concentration gradient (because it moves solutes from low to high concentration—where it’s already crowded) 0 Difference in solution concentrations = concentration gradient 0 Three types of active transport… Active Transport 1. Pump 0 Pump – a protein PUSHES molecules across the membrane Ex: the Sodium and Potassium (Na/K) Pump. YouTube: Na/K Pump Active Transport 2. Endocytosis 0 Endocytosis (endo=in): a pocket (vacuole) forms around a large molecule outside the cell and buds inward to release the material inside the cell. Active Transport 3. Exocytosis 0 Exocytosis (exo=out): a vacuole inside the cell fuses with the cell membrane and forces the material outside the cell. Animation