* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Animal Development and Homeotic Genes
Copy-number variation wikipedia , lookup
Public health genomics wikipedia , lookup
X-inactivation wikipedia , lookup
Neuronal ceroid lipofuscinosis wikipedia , lookup
Point mutation wikipedia , lookup
Epigenetics in learning and memory wikipedia , lookup
Long non-coding RNA wikipedia , lookup
Gene therapy wikipedia , lookup
Epigenetics of neurodegenerative diseases wikipedia , lookup
Minimal genome wikipedia , lookup
Protein moonlighting wikipedia , lookup
Gene therapy of the human retina wikipedia , lookup
Vectors in gene therapy wikipedia , lookup
Ridge (biology) wikipedia , lookup
History of genetic engineering wikipedia , lookup
Epigenetics of diabetes Type 2 wikipedia , lookup
Genomic imprinting wikipedia , lookup
Gene desert wikipedia , lookup
Genome evolution wikipedia , lookup
Helitron (biology) wikipedia , lookup
Gene nomenclature wikipedia , lookup
Biology and consumer behaviour wikipedia , lookup
Nutriepigenomics wikipedia , lookup
Polycomb Group Proteins and Cancer wikipedia , lookup
Site-specific recombinase technology wikipedia , lookup
Genome (book) wikipedia , lookup
Microevolution wikipedia , lookup
Therapeutic gene modulation wikipedia , lookup
Epigenetics of human development wikipedia , lookup
Gene expression programming wikipedia , lookup
Gene expression profiling wikipedia , lookup
Designer baby wikipedia , lookup
Animal Development and Homeotic Genes go to : http://www.dnaftb.org/37/ 1. What are the stages of fruit fly development? 2. When the embryo is developing, there are proteins concentrated at different places. These proteins (transcription factors) turn on specific __________________ __________________ needed for the next stage of development. 3. What do the embryonic genes do for the embryo? 4. What is a "gap" gene? 5. What is a pair-rule gene? 6. What are homeotic genes? 7. Why is it likely that ancestors of fruit flies had 2 pair of wings? What gene causes them to have only one pair of wings? 8. Fruit fly segments are essentially the same because they have the potential to make the same types of structures. It’s the correct expression of the homeotic genes that dictates which segment makes a particular type of structure. Explain this statement using the fruit fly example. You may want to study the picture as well. 9. Draw how the bithorax homeotic genes look on a chromosome. Now draw the fruit fly and color code which genes code for which structures on the fruit fly. You should focus on purple, green, and gray since this homeotic cluster codes for the specialization of thoracic and abdominal cell/proteins. 10. What is the homeobox, and how many of the SAME amino acids does the homeobox code for? 11. So after really studying the animation of those 60 amino acids (homeobox proteins), you should recognize that they are proteins that can be activators of gene expression or they can inhibit gene expression. Give an example of how the homeobox proteins can activate gene expression in fruit flies and how they can inhibit gene expression. 12. Are mammal’s bodies in segments like the fruit fly? 13. What are our homeotic genes called? 14. Draw the hox gene in mice and draw the mouse embryo. Color code each gene in the hox cluster and match it to the part of the mouse it codes for. Do this just like you did number 9. Describe each of the following mutant flies: kruppel mutant fushi tarazu mutant Ubx mutant Antp mutant Go to the link: "problem" 7. What will happen to an embryo that doesn't have BICOID protein? 8. What will happen if BICOID is overexpressed? 9. What kind of gene is HAIRY? 10. What kind of gene is EYELESS?