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Unit Plan – Biology Unit 1: Sex, variation and natural selection Lesson 1 2627/8 Topic Characteristics of living things Why is it all about SEX? DNA Molecule, Genes, chromosomes, proteins 2 2829/8 DNA Gametes 3 1-2/9 Discontinuous variation Activity Go over science skills test. Characteristics of living things worksheet and discussion of how these characteristics all support passing on of an individual’s genes. DNA – About the molecule worksheet Build model of DNA Monohybrid crosses Pre-test (10 minutes) Lab on PTC tasting Look at crossing of human monohybrid traits e.g. Knowledge and Skills - All students should: -List, identify and describe the characteristics of living organisms including reproduction, respiration, nutrition, excretion, growth, sensitivity and movement. -State that DNA is the chemical which stores the coded instructions. Self-assessment-check answers to worksheet. -Explain that genes are ‘coded instructions’ for making proteins. -List the components of a DNA nucleotide. -Describe how nucleotides are joined to create a double stranded DNA molecule. -Explain complementary base pairing and the bonding within a DNA molecule. -State that the genetic code is read as triplets and is universal. -Explain that changes in the genetic code can lead to mutations. -State that some mutations are responsible for heritable variations in populations Peer in groups -Design and build a model which accurately depicts the molecular structure of DNA -Describe the basic structure of chromosomes and where they are found in eukaryotic cells. -State the differences in the number of chromosomes in somatic(body) cells and gametes (sex cells) -Define the terms haploid and diploid -Explain the basic principles of meiosis and gamete formation -State that fertilization restores the diploid number. Ppt gametes/animation gametes and meiosis Monohybrid crosses 4 3-4/9 Assessment Formative -Measure and analyse variation in a population -Draw a histogram which depicts discontinuous variation. - Define the terms chromosome, DNA, gene, allele, genotype, phenotype, homozygous, heterozygous, dominant, recessive, and gamete. -Determine the frequencies of monohybrid traits in the class and compare them to theoretical values continued 5 5-8/9 Continuous variation tongue rolling, lobes, thumbs and mid-digit hair Lab on variation in bean sprouts and height Formative quiz on monohybrid crosses Formative-histogram 6 9-11/9 7 1215/9 8 1617/9 9 18/199 Natural Selection Natural selection Introduction to natural selection Tooth pick exercise Peppered moth and bacteria Summative-graph Formative dataresponse question -Explain how animals and plants adapt to specific features in their environment M & M activity Ref to Darwin’s finches Review. End of Unit test -Measure and analyze variation within a population. -Draw a histogram that depicts variation within a population. -Explain the differences between continuous and discontinuous variation. -Discuss that continuous variation is a result of both environmental and genetic influences -Explain how continuous variation can lead to normal distribution within a population. -Describe how variation in organisms leads to differential survival -State that natural selection leads to evolution of populations - Describe examples of how natural selection leads to evolution Summative Characteristics of Living Things There are 7 characteristics of living things: Movement Respiration Sensitivity Growth Reproduction Excretion Nutrition a) Match the following statements with each of the characteristics. Producing offspring Swimming, running, crawling, opening of flowers Releasing energy from food Responding to stimuli Eating and drinking/feeding Removing poisonous waste Increasing in size b) For each of the diagrams below state which characteristic of living things it shows. 3 4 DNA: Structure and Function The following program will help you to understand how the DNA molecule carries the chemical code for inheritance. Answer each question as you go by circling the letters or filling in the blanks. 1. Examine Fig. 1 that is a diagram of a short length of a DNA molecule. The DNA molecule is long and threadlike or string like. It is composed of two strands, or threads, that loosely twist about each other. The two long strands are connected by short rod like structures that are composed of bases. Which letter(s) indicate the long twisting strands? ( a b c d) Fig. 1 2. Which letter(s) in Fig. 1 indicate the rod like structures that join the long, twisting strands? _______ 3. If the twisted strands of DNA were untwisted, the model would look something like a ladder (as shown in Fig. 2). In the untwisted molecule, the long strands (sides of the ladder) are indicated by the letters ( a b c d ), and the connecting rod-like structures (the rungs of the ladder) are indicated by the letters ( a b c d ). Fig. 2 Fig. 3 4. Fig. 3 shows a close up view of one strand of the DNA molecule. Sugar molecules and phosphate molecules alternate in the strand. Do these groups also alternate in the second strand? (yes / no) 5. The sides of the ladder (the long strands) are made of alternating _________ groups and ____________ groups. 5 6. The structure labeled ______ is a strong chemical bond that joins the sugar and phosphate groups. 7. The rungs of the ladder consist of . 8. These rungs are connected to the groups on the sides of the ladder. 9. The structure labeled ______ is a strong chemical bond that joins the base to the sugar group. 10. Given your knowledge of the structure of DNA so far, what is wrong with the following figures? S P S P S P S P S P S P Fig. 4: S S P P S S P P S S P P S S P P Fig. 5: 11. The two rod structures that make up the rungs on the ladder are bases. These bases face each other in this fashion: Fig. 6 In this example, one of the bases that makes up a rung is labeled ____;the other is labeled _____. 6 12. While all of the rungs are made of two bases, not all of the rungs are alike. Some of the rungs are made of two other kinds of bases that called G and C, as shown below. Fig. 7 13. Examine Fig. 8 .This diagram shows a segment of a DNA molecule with six rungs. They are numbered 1 to 6. Rung 1 contains two bases. What are they? ________. This is called a base pair. Fig. 8 14. Rung 2 contains the base pair_________. 15. Rung 4 contains the base pair_________. 16. Rung 5 contains the base pair_________. 17. In Fig. 8, do any of the rungs contain an A – G base pair? (yes/no) _______ 18. Do any of the rungs contain a T – C base pair? (yes/no) _______ 19. Therefore, always base pairs with and always base pairs with . 20. The bases don’t physically join together by covalent bonds. Instead, they are attracted to one another due to their chemical structures. These attractions are called hydrogen bonds and are very weak compared to the covalent bonds that hold the sugar and phosphate groups together. These attractions are very specific and only allow A to form hydrogen bonds with T, and G to form hydrogen bonds with C. Specifically, A will form 2 hydrogen bonds with T, and G will form three hydrogen bonds with C. 21. How many total hydrogen bonds will there be in a section of DNA that contains 4 A-T base pairs? 7 22. How many total hydrogen bonds will there be in a section of DNA that contains 2 G-C base pairs? 23. How many total hydrogen bonds will there be in the section of DNA in Fig. 8? 24. DNA molecules control inheritance, and we also know that genes control inheritance. Would you suspect that there might be some relationship between DNA and genes? (yes/no) ______ 25. We also know that only the bases A,T,G,C that comprise the rungs of the ladder control the differences in heredity. When the order of these bases are changed, it (can affect/cannot affect) ______________ the heredity message that the genes transmit. 26. We know that there are thousands of genes in any one organism such as a human being and only four bases in the DNA molecule. If there are thousands of genes, and only four bases then one base (could be / could not be) ________________ one gene. 27. One base cannot be one gene. Then how can four bases be thousands of genes? The following approach is one explanation of this relationship. Imagine that each base is like a letter in our alphabet. There are 26 letters in the English alphabet, from A to Z. Most words are made of two or more letters, such as BAD, POT, PEAL, and POOL. However, other words can be made from the same letters simply by rearranging them. For example: BAD - DAB POT-TOP PEAL-LEAP POOL-LOOP 28. Thus, while the letters of the alphabet do not change, one word can be changed into another by ____________________ the letters. 29. A single gene is usually made up of hundreds of bases, and therefore the number of different genes that can be made using these four bases in almost limitless. For example, if genes were only two bases long (that is, two rungs on the ladder), you could have the following combinations: 30. A-T, A-G, A-C, A-A, T-A, T-G, T-C, T-T , G-A, G-C, G-T, G-G , C-A, C-G, C-T, or C-C or a total of combinations. This can be determined by the equation: combinations x = 4 , where 4 is the number of bases there are and x represents the number of bases in the gene. In the last example, there are 42 (or 4 x 4) = 16 combinations. 31. If genes were 3 bases long, how many different genes could there be? 43 = 32. How many different genes can be represented from the piece of DNA in Fig. 8? 33. A gene of 100 bases is considered to be a small gene. How many combinations of that gene are there? Get your calculators out! . Now consider that an average size gene is 1000 bases long and it is hardly a wonder that there is so much diversity around! 34. The instructions on a DNA strand are read in groups of three bases. To illustrate this, imagine this group of letters was a DNA strand. THEREDDOGATETHEFATCAT Reading in groups of three, the sentence would be: 8 35. As mentioned earlier, bases in the DNA can change, giving rise to new instructions that alter the heritable traits. Try changing the 19th letter in the sentence above to an R. Now what does the sentence say? . Does it still make sense? 36. Sometimes changes in the DNA can lead to a disaster as far as clear instructions go. Try adding an E after the O in the sentence and read it in groups of three. Does it make any sense? Build a DNA Model In your groups, based on your knowledge of DNA you need to design and build a 3-dimensional model which accurately represents DNA as a molecule. You can use any materials you wish. Basic materials available in class will be: Scissors Glue Cellotape Paper Your model will be assessed by your peers using the following rubric: Rubric for 3-D DNA MODEL Names: Not at all Partially Completely Has two strands each with at least 5 nucleotides shown in each 0 1 2 Each strand shows correct arrangement of sugar, phosphate and base 0 1 2 Is a double helix (Shows at least 1 twist) 0 1 2 Shows correct complimentary base-pairing 0 1 2 Correct number of hydrogen bonds between base-pairs 0 1 2 Total /10 9 A Variety of Gametes Gametes (sex cells) are produced as a result of meiosis in organs called gonads. Gametes are haploid so that when male and female gametes come together in fertilisation the diploid number is restored. There are a variety of gametes produced by different organisms. Search the internet to complete the table below: Name of organism Human Chicken Goat Tomato Rice Diploid number of chromosomes in somatic cells 46 Haploid number of chromosomes in gametes 23 Name of male gamete Name of female gamete sperm ovum Discontinuous Variation Characteristics showing discontinuous variation fall into a few very distinct (no overlap) classes. These variations result from genetic factors, usually one or two genes. Environmental factors generally do not play any part in this type of variation. The ability to taste an organic chemical PTC (phenylthiocarbamide) is determined be a single gene with two alleles; non-tasters (t-recessive) and tasters (T-dominant). About 70% of the general population has the ability to taste PTC. You will be given a piece of filter paper which has PTC soaked into it. Place it in your mouth and write down if you taste anything or not on the piece of scrap paper. Record the number of people in the class who can/cannot taste PTC. Draw a histogram of the results on graph paper. What kind of variation does this show? 10 Some definitions you will find helpful in genetics Allele One specific form of a gene, differing from other alleles by one or a few bases only and occupying the same gene locus/position as other alleles of the gene. Gene A heritable (that can be inherited - from parents) factor that controls a specific characteristic, consisting of a length of DNA occupying a position on a chromosome known as a locus. Genotype The alleles (versions of genes) possessed by an organism. Phenotype All the characteristics of an organism determined by the genotype and the environment. Dominant allele An allele which has the same effect on the phenotype (you) whether it is present in the homozygous or heterozygous state(presents in you if you get dominant allele from either mom or dad). Recessive allele An allele which only has an effect on the phenotype when present in the homozygous state (recessive from mom and recessive from dad). Homozygous Having two identical alleles of a gene. Heterozygous Having two different alleles of a gene. Haploid (n) The chromosome set having only one member of each chromosome pair Diploid (2n) Individual or cell having two copies of each chromosome pair, one from the mother and the other from the father. 11 Monohybrid Crosses. 12 13 Monohybrid Crosses – Problems Please answer your questions on a separate piece of paper. 1. In dogs, wire hair (H) is dominant over smooth (h). In a cross of a homozygous wire-haired dog with a smooth-haired dog, what will be the phenotype of the puppies? 2. In guinea pigs, black coat color is dominant over white. If a heterozygous blackcoated guinea pig is mated with a white coated guinea pig, how many different phenotypes with respect to coat color could be expected in the offspring? 3. In Pea plants the alleles for tall plants (T) is dominant over the alleles for short plants (t). When two pea plants are crossed, 92 tall plants and 31 short plants are produced. The genotypes of the parent plants are? 4. The ability to curl your tongue up on the sides (R, tongue rolling) is dominant to not being able to roll your tongue. A woman who can roll her tongue marries a man who cannot. Their first child has his father's phenotype. What are the genotypes of the mother, father, and child? 5. Saguaro cacti are very tall cylindrical plants that usually have two L-shaped arms, one on each side. Suppose you lived in southern Arizona in the United States where the Saguaro cactus is common and you happen to have one growing in your yard. Your Saguaro has two arms but one is longer than the other. Now, assume that arm length in these cacti is controlled by a single gene with arms of the same length (A) being dominant to arms of different lengths. a. What is the genotype of your cactus? b. Is it possible that the parents of your cactus could both have arms of the same length? If so, what are their genotypes? c. Suppose you cross your cactus with that of your neighbor which has arms of the same length. Your great grandchildren (it takes a Saguaro cactus a long time to mature) find that half of the resulting offspring have arms the same length and half have arms of different lengths. Use a Punnett square to demonstrate the genotype of your neighbor's cactus. 14 Genetic Traits Inventory (from http://gslc.genetics.utah.edu and http://www.woodrow.org) Traits are observable characteristics. While each of us shares some of our traits with many other people, the combination of all our individual traits is what makes us unique. All the traits in your body are determined by bits of DNA called genes. Hundreds of genes together form chromosomes, which are found in the nucleus of cells. Cells have 2 copies of each gene because both mother and father give one copy at fertilization. Most genes have two or more variations. For example, the gene for your earlobe shape has two versions called alleles – attached or free hanging (see diagram below). These versions, as in many genes, have a dominant and a recessive alleles. In this example, the free earlobe is dominant to attached. If an individual has 2 versions for free hanging lobes (dominant), then their earlobes will be free. If an individual has 2 versions for attached lobes (recessive), then their earlobes will be attached. But if they have one of each, then they will have free hanging earlobes because it is the dominant version. In this investigation you will examine some of the traits you have and compare them with the other students in the class. Ear lobe attachment: (See Fig. 1) The ear lobes may either hang free or be attached directly to the side of the head. The allele for the free or unattached ear lobe trait is dominant (F), while attached earlobes are caused by having two recessive alleles (ff). Tongue rolling: (See Fig. 2) Some people have the ability to roll their tongue into a distinct U-shape when they extend their tongue from their mouth. This ability to roll the tongue is due to a dominant allele (R). Those who have the two recessive alleles (rr) can only curve their tongue slightly. Hitchhiker's thumb: (See Fig. 3) People with two recessive alleles (tt) for hitchhiker's thumb can bend the distal joint of their thumb back so that it forms an angle of almost 45 degrees. This would be hyperextension of the thumb. People with a dominant allele (T) cannot do this. Mid-digital hair: (See Fig. 4) The mid-digital hair trait is determined by a dominant allele (D) for each finger causing hair to grow on the top of that finger. The trait is carried by a set of five alleles and will cause hair to grow on one finger, two fingers, etc., depending on what allele you inherit. People who have no hair on the digital part of their fingers carry all recessive alleles (dd). Gender: Females have two X chromosomes, while males have an X and a Y chromosome. Maleness is determined by a special region of the Y chromosome. Femaleness results from the lack of this region. Handedness: While this may be more complicated than one gene, some scientists thought that righthanded was dominant to left-handed. Hairline shape (see Fig 5). The shape of the hairline can be a widow’s peak (dominant) or a straight line (recessive). Hand clasping: Without thinking about it too much, clasp your hands together. People with a dominant allele affecting this will have their left thumb on top, while those with both recessive alleles will have the right thumb on top. 15 Fig 5 1) Complete the following table using the data from the class. Trait Yes No % Frequency of dominant trait Free ear lobes? Tongue rolling? Hitchhiker’s thumb? Mid-digital hair? Female? Right-handed? Widow’s peak? Left thumb on top? 2) Find the frequency of each trait and enter it into the last column. The frequency of each trait can be determined using the following formula: Number of students with the trait X 100 = % frequency. Number of students in the class 3) Compare the frequency in the class of each gene with the frequency of the traits in the general population in the table below and calculate % difference with class data. What kind of variation is shown by each of these traits? Trait Free earlobes Tongue Rolling Hitchhiker’s thumb Mid-digital Hair Gender Handedness Hairline Hand clasping Frequencies Free – 60%; Attached – 40% Rollers – 70%; Non-rollers – 30% Straight thumb – 75%; Hitchhiker’s – 25% With hair – 80%; No hair – 20% Males – 50%; Females – 50% Right handed – 93%; Left handed – 7% Widow’s peak – 90%; No widow’s peak – 10% Left thumb on top – 55%; Right thumb on top – 44% 16 Variation Lab Introduction: Variation is common in all species and is caused by meiosis, mutation and sexual reproduction. Some variations seem to have no apparent survival advantage or disadvantage, or others may eventually prove to be advantageous and allow the individual to withstand some environmental change. When studying variations of a characteristic, a biologist measures each variation and examines the frequency and the degree to which the variation occurs within a population. In this investigation, you will determine the mode, which the most commonly occurring measurement found among the variations in the population being studied. You will then graph your findings by drawing a frequency distribution curve, a graph that illustrates the range of variations for the trait and shows the number of individuals that exhibit each variation. Part A – Bean Sprout Height 1. Collect 20 mung bean sprouts. They have been grown under identical conditions in a dark moist area for several days. 2. Measure to the nearest millimeter the shoot of each bean from the root tip to the shoot tip. Record your measurement in the table below. Add uncertainties. Obtain 20 more measurements from another group. Sprout Length (mm) 1 2 3 4 5 6 7 8 9 10 Sprout Length (mm) Sprout 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 Length (mm) Sprout Length (mm) 31 32 33 34 35 36 37 38 39 40 Group the lengths of the sprouts into 5 mm (or other suitable) ranges or bins (46-50 mm, 51-55 mm, 56-60 mm, etc). Construct a frequency table in the space below: 17 Graph your results on graph paper to show a frequency distribution curve (histogram). Put number of sprouts (frequency) falling in each range or bin on the Y Axis and the ranges (bins) of the length of sprouts on the X-axis. Questions: 1. What is the length of the shortest bean sprout? 2. What is the length of the longest bean sprout? 3. What is the range of your measurements? 4. What is the mode (the most common range/bin measurement) for length among your bean sprouts? 5. In mm what is the difference between the lowest measurement and the mode? 6. What is the difference between the highest measurement and the mode? 7. Which measurement tells you the most about a population with regard to a particular trait; the lowest measurement, the highest measurement or the mode? Conclusion and Questions: 1. What shape does a distribution curve generally take? 2. What advantages and disadvantages do you think the longest bean sprouts have for survival? 3. What kind of variation does bean sprout length show? Explain. 4. Identify some factors not related to genetics that might have affected the length of each bean sprout. Extension Activity Height of 9th Graders-see moodle 18 The Peppered Moth: An Evolutionary Example of Adaptation and Survival One of the most studied examples of adaptation is the dark- and light-colored peppered moth of England. The peppered moth, Biston betularia, occurs in two color forms: (1) gray with dark flecks, and (2) solid black. Like most moths, peppered moths are active at night, and rest during the day. Although all their hiding places are not well known, peppered moths may rest on tree trunks and in the overlying canopy. In pre-industrial England, most of the peppered moths were speckled gray, much like the trees on which the peppered moths rested during the day. The black moths were fewer in number. However, with the Industrial Revolution came factories, which produced huge volumes of polluting, black soot produced by the burning of coal. In a short time, the black-colored moths dominated the population, and speckled gray moths were fewer in number. (A) Pre-Industrial Revolution (B) During Industrial Revolution 19 Being eaten by a bird is the primary threat to a peppered moth. In industrial areas, the black moths appear to have avoided being eaten. They survived better, and reproduced more, or had what biologists call a higher “fitness”. Since more of the black parents lived to reproduce, their population numbers increased. After many moth generations, almost all of the moths in industrial areas were black. Black coloration is considered to be, therefore, an adaptation to an environment with black tree trunks. They evolved through natural selection because black individuals have a higher fitness in areas where the tree trunks are black than do the gray moths. It is important to note that it is not the individuals who adapted. Peppered moths are black or gray because of their genetics. It is the result of a population’s fitness within a certain environment that gives them an “edge” over another population. With this information in mind, conduct the lab activity. You will see for yourself exactly what happened to the peppered moth populations, as England became an industrialized nation. WANT TO KNOW MORE???? Follow these links for more about the peppered moth: (1) www.utm.edu/~rirwin/moth.htm (2) www.gen.umn.edu/faculty_staff/hatch/1131/Evolution/peppered_moth.html (3) http://biocrs.biomed.brown.edu/Elephant%20stuff/Chapters/Ch%2014/Moths/Moth-Update.html (this last one is complex, but presents some interesting and updates concerning peppered moth research) 20 ACTIVITY: THE PEPPERED MOTH: How Adaptations Aid Survival and Affect Population Size The table below represents data from a ten-year study of two varieties of the same species of peppered moth. The number represents moths captured in traps for ten consecutive years. The traps were located in the same area each year. Year 1 2 3 4 5 6 7 8 9 10 Numbers of light Moths Captured 556 537 484 392 246 225 193 147 84 56 Numbers of dark moths Captured 64 112 198 210 281 357 412 503 594 638 Using this data provided construct a graph (think of the most suitable way) comparing the numbers of each variety of peppered moths. QUESTIONS AND SUMMARY: 1. What preys on the peppered moths? 2. If the bark of the trees is dark and the moths that rest there are light what will happen to the moths? 3. What could have caused the first moths to change from a light variety to a dark variety? 4. What event caused the tree trunks of many trees in England to turn from light to dark? 5. Which variety of moth increased of the ten-year period? 6. Using the data on the graph, draw a conclusion concerning the population of peppered moths in the sampled area of England. 7. Explain the reason for the increase in the number of dark colored moths. 8. What means could be used to return the environment of the peppered moth to its original state? 9. What effect would cleaning up the environment have on the moths? 10. What kind of variation is shown by the peppered moths? 21 Darwin’s Finches Charles Darwin visited the Galapogos Islands in 1835 and gathered data on finches that were living there. When he returned to London, he looked carefully at his data and came to the conclusion that all the birds were closely related and it led him to develop his theory of natural selection. A few million years ago a species of finch migrated to the Galapogos Islands from mainland South or central America. From this one species came 13-14 other species to exploit particular niches within the islands through a process known as adaptive radiation. Adaptive radiation occurs when the niche exerts selection pressures that push populations in particular directions. In this case the finches have become adapted to eating seeds, insects, flowers, sucking the blood of sea birds and leaves. It is thought that changes in climate caused a change in the type of food that was available, hence the beak structure that was best adapted to a particular type of food survived and reproduced while the remainder died. [source, accessed June 2008: http://nhsadvancedbiology.blogspot.com/2008/02/darwins-finches-activity.html] Questions. Choose two of the species of finch and describe how their beaks are best adapted to the food that they eat. 22 Activity: Survival of the best beak! This simulation exercise is designed to demonstrate how the best adapted beak for a particular food type allows that species to survive and reproduce. In groups of 10 you are provided a tray of M & M’s and the following “beaks”: Chop sticks; fork; spoon, forceps, knife, toothpick. 1) Each group member is allocated a type of beak. 2) You are then given 30s to collect as many M & M’s as you can using ONLY your “beak”. Do not interfere with anyone else. 3) For each beak type record the number M & M’s collected. 4) If you collected 15 you survive and can reproduce; if you did not you die (you then become an offspring of a surviving beak type) 5) Return the M & M’s to the bowl 6) Repeat steps 2) to 4) three more times. There has been a change in the climate and the type of food available now is popcorn. Repeat 1) to 6) above. Processing your data a) Graph the number of M & M’s collected against the beak type after the first “feeding”. b) Graph the number of pieces of popcorn collected against the beak type after the first “feeding”. c) Graph (on the same set of axes) the number of each type of beak surviving after the third generation and after the 4th generation. Questions i) Which “beak” was best adapted for M & M’s? Explain. ii) Which “beak” was best adapted for the popcorn? Explain. 23 Natural Selection: The Key ideas Use the list of words below to complete the paragraph. struggle for survival least adapted mutation change best suited sexual reproduction natural selection evolve reproduce inherited extinct competition meiosis survival of the fittest offspring genes ………………………………………and ……………………(3 things) result in variation in offspring. Organisms tend to produce more……………… than the environment can support. This leads to a………………………………..or …………….. Those organisms which …………………characteristics that are …………………….. to the environment survive and can………………. And pass on their advantageous ……….. ; those that are …………………….. die off and may become………………….. This is sometimes referred to as……………………….. The process of some organisms surviving whilst others die off is known as……………………. Species can…………….., where the characteristics of a population ……………………to suit the environment over a long period of time through natural selection. This often occurs in response to environmental change. 24