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Page 1 of 5 IB Biology--Chromosome Review Activity Name_________________________Period____Date___ Use BioNinja site: ib.bioninja.com.au/standard-level/topic-3-genetics/32-chromosomes/ And 2 telomere sites - learn.genetics.utah.edu › Basic Genetics and https://www.hhmi.org/biointeractive/search?text=telomeres&sort_by=search_api_releva nce&redirect=1 to complete the following questions : 1. Since the DNA of prokaryotes lacks histones it is termed _____________________. 2. How does eukaryote and prokaryote DNA compare? 3. Recall nucleosome and nucleoid structure and draw below. 4. Look @ the visuals from the BioNinja site and describe what appears to be the basic difference between active and less active genes? What is preventing the less active genes from transcribing? 5. _______________________are much more condensed by supercoiling than chromatin. 6. What produces banding patterns? 7. Distinguish between centromeres, p arms and q arms. Page 2 of 5 8. The ______________is the specified position of a gene on a chromosome. 9. Use the 10p42 reference to a chromosome to identify the significance of the 10, the p, and the 42 . 10. What is the importance of the q3.12 locus on human chromosome # 7? How does this affect a human that is homozygous for this allele? 11. Using the Human Genome Landmarks Poster:Chromosome viewer-look up chromosome # 13 and identify 3 genes. 12. What is the locus of coagulation factor VIII gene(F8) in a house mouse? 13. How are homologous chromosomes alike and different? Page 3 of 5 14. Which cells are haploid and which are diploid? 15. ___________________ are the X and Y chromosomes in humans. 16. What, in terms of chromosome levels, determines gender in humans? 17. Why is 3H-T used in autoradiography of DNA and what is the purpose of 3H-U ? 18. Show a theta structure and a zipped and unzipped portions . 19. What is a replication bubble? 20. What does the bidirectional nature of DNA imply? 21. Give an example of how chromosome # does not indicate complexity. 22. What is the longest known genome? Page 4 of 5 23. Why may plant genomes be so large? 24. Use drawings to compare telocentric ,metacentric , submetacentric , and acrocentric chromosomes .Give 1 example of the last 3 in humans. 25. Compare X-0, Z-W, and haploid-diploid system of sex determination . 26. What is a telomere and give a practical analogy? 27. What exactly does a telomere prevent on a DNA strand? 28. How does telomerase affect the longevity of cells? Page 5 of 5 29. Why do telomeres get shorter? 30. What are the connections between telomeres and aging?