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SCHOOL SYLLABUS LINKS Cycles COMMON KEY LEARNING POINTS Characteristics, differences and similarities of animal, plant, bacteria and fungal cells. DNA LAB PROGRAMMES Diversity of Cells Differences in parts and functions between animal and plant cells. Systems Understanding of inheritance – many characteristics of an organism are passed on from parents to offspring. Genes and Our Traits Function of DNA and its role in the cell system. DNA Basics Identification of animal and plant cell parts and functions. Diversity of Cells Electrical circuit and current flow application in DNA electrophoresis. DNA Detectives Genes and our Traits DNA Basics DNA Detectives Bacteria Outbreak Diversity of Cells DNA Basics / Genes and our Traits DNA Detectives / Bacteria Outbreak SCHOOL SYLLABUS LINKS COMMON KEY LEARNING POINTS DNA LAB PROGRAMMES Lower Secondary Diversity of living things Awareness that bacteria could have beneficial or harmful effects. Bacteria and Health/ Food Microbiology Human digestive system Importance of hygiene habits and food handling practices to prevent food-borne diseases. Bacteria and Health Role of amylase in digestion. Proteins Revealed and Reviewed Hygienic practices when handling food. Bacteria and Health Identify cell structures and organelles of different organisms. Life in Micro Relationship between cell function (transport of oxygen) and cell structure (red blood cells). Genetic Diseases Biuret and starch test. Proteins Revealed and Reviewed Food and Consumer Education Food and kitchen safety O Level Biology Cell structure and organisation Biological molecules - proteins Effects of temperature on rate of enzyme reaction. Enzyme mode of action, key components involved in a catalytic reaction. Amazing Enzymes Effects of substrate concentrate on rate of enzyme reaction. Nutrition in humans Function of amylase in digestion. Proteins Revealed and Reviewed Transport in humans Role of red blood cells in oxygen transport and diseases (thalassaemia and sickle cell anaemia). Genetic Diseases Different ABO blood groups and possible combinations for donor and recipient in blood transfusions. DNA and Life Function of the brain and neurons. The Brain Connection Co-ordination and response in humans Function of the brain and spinal cord in producing a co-ordinated response. SCHOOL SYLLABUS LINKS COMMON KEY LEARNING POINTS DNA LAB PROGRAMMES Cell Division Identify the main stages of mitosis and meiosis. Life in Micro Molecular genetics Structure of DNA, complementary base pairing rule. DNA and Life/ DNA in Forensic Science/ Genetic Diseases/ Finding the lost Princess/ DNA: Cracking the Code of Life/ Developing a Scientist Skillset Relationship between DNA, genes and chromosomes. DNA and Life/ Genetic Diseases/ DNA: Cracking the Code of Life DNA is used to carry the genetic code, which is used to synthesise specific polypeptides. DNA: Cracking the Code of Life Transfer of genes between organisms. Bacteria Transformation Applications of genetic engineering (such as insulin production). Inheritance Ethical and social implications of genetic engineering. Bacteria Transformation/ Science and Society Define a gene and distinguish between gene and allele. Genetic Diseases Understand the terms dominant, recessive, homozygous, heterozygous, phenotype and genotype. Predict the results of simple crosses using genetic diagrams involving monohybrid inheritance. Inheritance of the ABO blood group phenotypes. DNA and Life Inheritance of genetic information from parent to offspring. Genetic Diseases/ Finding the Lost Princess Explain the determination of gender in humans. DNA and Life/ Genetic Diseases Mutation of a gene that results in a change in structure. Genetic Diseases (sickle cell anaemia)/ DNA: Cracking the Code of Life Nutrients from food Role of enzymes in the digestion of food. Proteins Revealed and Reviewed Food health and safety Sources of proteins. Proteins Revealed and Reviewed N(T) Science Food tests for starch and protein. Beneficial action of microbes on food. Food Microbiology Digestion Effect of temperature on the rate of enzyme reaction Proteins Revealed and Reviewed Staying healthy Bacteria and antibiotic resistance. Bacteria and Health Inheritance of thalassaemia from parents. Genetic Diseases SCHOOL SYLLABUS LINKS COMMON KEY LEARNING POINTS DNA LAB PROGRAMMES History Soviet Union and Eastern Europe Events within Russia in 1917 – the Romanov family. Bacteria Transformation Finding the Lost Princess SCHOOL SYLLABUS LINKS H1 Biology Core Topics: Cellular functions COMMON KEY LEARNING POINTS Mode of action of enzymes DNA LAB PROGRAMMES Amazing Enzymes Effect of substrate concentration on rate of reaction DNA and genomics Evolution H1 Biology Application Topics: Isolating, cloning and sequencing DNA Application of molecular and cell biology H2 Biology Core Topics: Cellular functions Structure and role of DNA Bacteria Transformation/ PTC/ Forensic Analysis/ Genetic Engineering Change in DNA sequence affects phenotype PTC/ Bacteria Transformation Variation and natural selection PTC Function of restriction enzymes PTC/ Genetic Engineering Formation of recombinant DNA molecule (bacterial plasmid) and using it as a DNA cloning vector to insert Eukaryotic genes in E. coli Bacteria Transformation/ Genetic Engineering PCR and gel electrophoresis PTC/ Forensic Analysis/ Genetic Engineering Ethical implications of genetic testing Science and Society Significance of genetic engineering Bacteria Transformation/ Genetic Engineering Mode of action of enzymes Amazing Enzymes Effect of substrate concentration on the rate of enzyme-catalysed reaction. Genetics and inheritance Structure and role of DNA Bacteria Transformation/ PTC/ Forensic Analysis/ Genetic Engineering Structure of prokaryotic and eukaryotic genomes Bacteria Transformation/ Genetic Engineering Regulation of gene expression with operons Genetic Engineering Principles and procedures of PCR and gel electrophoresis PTC/ Forensic Analysis/ Genetic Engineering How genotype is linked to phenotype Bacteria Transformation/ PTC SCHOOL SYLLABUS LINKS COMMON KEY LEARNING POINTS DNA LAB PROGRAMMES Biological evolution Variation and natural selection PTC H3 Biology – Proteomics Analytical techniques Use of UV absorbance spectroscopy Amazing Enzymes Application of bioinformatics to perform nucleotide homology searches PTC Mechanism of enzyme action Amazing Enzymes Protein structure and function Det DNA ective aits r Tr u o “Pupils are able to see DNA; they are able to see the relation between what they learn in school and how it affects in real life”. Bacteria and H Fo lth ea “Covered real life diseases which students can relate to.” “Simplified explanation for people who totally did not know about bacteria.” students’ interest in the sciences.” “Students enjoyed casting the gel and solving the crime. It was engaging for the students and created awareness among them about the different techniques involved in forensic science.” nce and S cie “The variation in activities kept the students engaged.” PTC – The “Bit te of Super-ta Life ste r” es ic Diseas net Ge “The discussion on the use of GMO, its issues and implications were very interesting and helped to inject a real life application.” c orensi Science nF i NA “Helpful in sparking iety oc Analysis DNA sic Pr n re formation ans r T D “Provides learning beyond textbook.” “Many topics were covered and these could serve as introductory courses for the students who are in JC1, eg. micropipetting skills, VNTR vs STR, PCR.” “DNA model making helped them visualise the DNA structure better.” A and Life DN Bacte ria Genes and “Interactive and engaging. Students are able to get hands-on experience learning about cells and microscope which they may not get in school.” S “Sparks the interests of students on the topic of cells.” g ilin of A Basics DN “Very authentic case that is able to engage the pupils and evoke their curiosity.” “Fantastic facilities and equipment. Hard to do PCR in school!” “Fits IB diploma syllabus for Biology.” rs Div ers s lls f Ce o ity in Micro Life “Learning about the brain in greater detail.” tors uca d rE Ou “The instructor was EXCELLENT, very informative, patient and organised.” “The instructor is knowledgeable and infused the lesson with many stories related to today's lesson. This piqued the pupils' interest in Science.” “Instructions given were very clear, simple and direct. In-depth learning and clarity of explanation by instructor.” “Very good instructor – very enthusiastic!” “Engaging, organised, good classroom management, humorous yet firm”. netic Engine Ge e g rin The Br ai onnection nC “The hands-on activities were helpful for the students to see more than what there is in their textbooks.” “Thorough, step by step instruction through the processes; directly linked to syllabus.”