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PART I Total Value: 75% Instructions: Shade the letter of the correct answer on the computer scorable answer sheet provided. 1. Which part of the nervous system is made up of the brain and spinal cord? T (A) (B) (C) (D) 2. Which structure protects the brain? (A) (B) T (C) (D) 3. A B C D Which describes the movement of ions by the sodium-potassium pump? (A) T (B) (C) (D) 5. hypothalamus medulla meninges pons Which structure directly controls a person’s ability to think about a question and answer it correctly? T (A) (B) (C) (D) 4. central parasympathetic peripheral sympathetic less sodium out than potassium in more sodium out than potassium in same sodium in as potassium out same sodium out as potassium in What type of compounds are acetylcholine and dopamine? (A) T (B) (C) (D) depressants neurotransmitters poisonous drugs stimulants Page 1 of 21 Answer Key: Biology 3201 August 2009 6. A researcher used electrical stimulation of a neuron to cause a response in muscle tissue and collected the data below. What can be concluded from this experiment? Electronic Stimuli (mV) Muscle Response 10 none 20 none 30 none 40 contraction 50 contraction Stimulation Response T (A) above threshold contraction (B) above threshold mild response (C) below threshold contraction (D) below threshold mild response Item #7 was dropped. 7. The diagram below shows portions of two neurons in a person’s brain. If a stimulus has reached the synapse, which is most likely represented by X? (A) (B) (C) (D) 8. Which drug is classified as a depressant? T (A) (B) (C) (D) 9. acetylcholine cholinesterase dopamine norepinephrine alcohol caffeine ecstasy nicotine What is the correct order of the path of light through the eye? (A) T (B) (C) (D) cornea ! lens ! vitreous humor ! pupil ! retina cornea ! pupil ! lens ! vitreous humor ! retina lens ! pupil ! cornea ! vitreous humor ! retina retina ! vitreous humor ! lens ! pupil ! cornea Answer Key: Biology 3201 August 2009 Page 2 of 21 10. Which part of the eye contains rods and cones? (A) (B) T (C) (D) 11. Which hormone is released from the pineal gland? (A) (B) T (C) (D) 12. ADH and FSH aldosterone and cortisol GH and GnRH oxytocin and thymosin What is the target organ for the hormone insulin? (A) (B) (C) T (D) 15. creates a second messenger effects cells to change shape interacts with DNA in the nuclei of cells triggers nerve impulses in cells Which hormones are produced in the adrenal gland? (A) T (B) (C) (D) 14. ADH FSH melatonin oxytocin When going through puberty, how does testosterone put hair on a boy’s chest? (A) (B) T (C) (D) 13. A B C D adrenal cortex heart kidney liver A tumour detected on the thyroid gland inhibits thyroid function. What is the effect on thyroxin and thyroid-stimulating hormone (TSH)? Thyroxin TSH T (A) low high (B) low low (C) high high (D) high low Page 3 of 21 Answer Key: Biology 3201 August 2009 16. What are chromatids? (A) (B) T (C) (D) 17. Why might a doctor suggest radiation as the best treatment option for a patient diagnosed with a localized cancerous tumour? (A) (B) T (C) (D) 18. 19. Prophase I Prophase II (A) 1 2 (B) 1 4 T (C) 2 1 (D) 4 1 What is true of a clone? both are produced in equal numbers both are the same size both have motility both have the same number of chromosomes Why might stem cells have the potential to decrease Parkinson’s symptoms? T (A) (B) (C) (D) 22. has different chromosome numbers is produced by meiosis is produced by mitosis results from sexual reproduction How are human sperm and eggs similar? (A) (B) (C) T (D) 21. can be administered at home has no side effects is focused on the affected area only will affect all of the body cells If the DNA per cell is measured during each stage of meiosis, which represents the ratio of DNA in prophase I to the DNA in prophase II? (A) (B) T (C) (D) 20. bacterial chromosomes dense patches within the nucleus duplicate copies of a chromosome prokaryotic nuclei They can become neurons that produce dopamine in the brain. They cause existing brain cells to produce dopamine. They decrease the amount of dopamine reducing enzymes. They increase the effectiveness of dopamine receptors in the brain. In which part of the flower does both meiosis and fertilization occur? (A) (B) T (C) (D) anther filament ovule stigma Answer Key: Biology 3201 August 2009 Page 4 of 21 23. Where are sperm produced? (A) (B) T (C) (D) 24. Which structure is surgically altered by a vasectomy? T (A) (B) (C) (D) 25. A B C D Which structure is affected by the secretion of progesterone? (A) T (B) (C) (D) 26. interstitial cells pituitary gland seminiferous tubules testes wall A B C D Which individual is in the follicular stage of the menstrual cycle? Hormone Individual T (A) (B) (C) (D) Progesterone Estrogen 1 low high 2 low low 3 high high 4 high low 1 2 3 4 Page 5 of 21 Answer Key: Biology 3201 August 2009 27. Which process occurs in the human female reproductive system? (A) (B) (C) T (D) 28. Which bacterial infection may not present symptoms at all or can lead to painful urination, penile or vaginal discharge? (A) T (B) (C) (D) 29. A B C D Why might a man be infertile if he is exposed to toxic chemicals, radiation and has overheated testicles? T (A) (B) (C) (D) 32. artificial insemination contraception cryopreservation in vitro fertilization In which structure does gas exchange between the mother and fetus occur? (A) (B) (C) T (D) 31. AIDS chlamydia genital herpes hepatitis A woman has blocked oviducts but produces healthy eggs. Which would allow her to conceive a child? (A) (B) (C) T (D) 30. external fertilization of gametes production of milk for the developing embryo production of zygotes in ovaries transport of oxygen through a placenta to a fetus abnormal sperm production endometriosis obstructed oviduct obstructed vas deferens What form of birth control is 100% effective? T (A) (B) (C) (D) abstinence birth control pill male condom rhythm method Answer Key: Biology 3201 August 2009 Page 6 of 21 33. Which structure does the allantois develop into? (A) (B) (C) T (D) 34. A 42 year old woman, who is eight weeks pregnant, is concerned about the possibility of genetic abnormalities in the fetus and wants to be tested immediately. Which is the best technique to use? (A) T (B) (C) (D) 35. hybrid tall × hybrid tall hybrid tall × pure tall pure short × pure short pure tall × pure short Eye colour for fruit flies is determined by genes X, Y and Z. Which is illustrated if X produces black eyes, Y produces brown eyes and Z produces magenta (purple) eyes? (A) (B) T (C) (D) 39. alleles chromatids hybrids sub units How did Mendel obtain the F1 generation of all hybrid tall pea plants? (A) (B) (C) T (D) 38. afterbirth amniotic sac placenta umbilical cord Which are alternate forms of genes? T (A) (B) (C) (D) 37. amniocentesis chorionic villi sampling fetoscopy ultrasound Which structure produces the navel (belly button)? (A) (B) (C) T (D) 36. amniotic fluid chorionic villi placenta umbilical cord blood vessels co-dominance incomplete dominance multiple alleles polygenic inheritance Which type of inheritance causes variation in height and skin colour in humans? (A) (B) (C) T (D) co-dominance incomplete dominance multiple alleles polygenic inheritance Page 7 of 21 Answer Key: Biology 3201 August 2009 40. What is the probability of parents having the following three children: two boys in a row followed by a daughter? (A) T (B) (C) (D) 41. Which explains how a cross between two grey mice can produce black mice, grey mice and white mice? (A) T (B) (C) (D) 42. anaphase of mitosis anaphase II of meiosis prophase of mitosis prophase I of meiosis A baby boy inherits a recessive allele from his mother. In which circumstance would he most likely show the trait coded for by the recessive allele? (A) T (B) (C) (D) 46. Gene pairs always sort in the same order. Gene pairs sort randomly and independently from each other. One allele is always dominant. Sister chromatids separate during gamete formation. Where does crossing over occur? (A) (B) (C) T (D) 45. concept of codons double helix Law of Dominance sex-linked traits What does the Law of Independent Assortment state? (A) T (B) (C) (D) 44. Crossing over occurs between white and black alleles. Inheritance involves alleles that are incompletely dominant. Mutations occur during gamete formation. Non-disjunction results in the production of abnormal offspring. What is one of Morgan’s major contributions to the field of genetics? (A) (B) (C) T (D) 43. 1 16 1 8 1 4 1 2 The allele is on an autosomal chromosome. The allele is on the X chromosome. The allele is on the Y chromosome. The allele undergoes a mutation. What percent of guanine would be found in a strand of DNA containing 28% cytosine? (A) T (B) (C) (D) 22% 28% 44% 56% Answer Key: Biology 3201 August 2009 Page 8 of 21 47. What are the components of DNA? T (A) (B) (C) (D) 48. phosphate group, nitrogenous base, deoxyribose sugar phosphate group, nitrogenous base, ribose sugar phosphate group, polypeptides, deoxyribose sugar phosphate group, polypeptides, ribose sugar Which is a function of DNA polymerase? (A) (B) T (C) (D) cleaves and unwinds the double helix joins Okazaki fragments together proofreads base pairing synthesizes an RNA primer to begin elongation Use the diagram below to answer questions 49 and 50. 49. Which molecule acts as a template for the production of structure D? (A) (B) T (C) (D) 50. amino acids dipeptides DNA RNA What type of structure would be partially formed by molecules E, F and G? (A) T (B) (C) (D) DNA polypeptide polysaccharide RNA Page 9 of 21 Answer Key: Biology 3201 August 2009 Amino Acids coded by mRNA Codons First Letter Second Letter U C A G Third Letter phenylalanine serine tyrosine cysteine U phenylalanine serine tyrosine cysteine C leucine serine STOP STOP A leucine serine STOP tryptophan G leucine proline histidine arginine U leucine proline histidine arginine C leucine proline glutamine arginine A leucine proline glutamine arginine G isoleucine threonine asparagine serine U isoleucine threonine asparagine serine C isoleucine threonine lysine arginine A START/ methionine threonine lysine arginine G valine alanine aspartate glycine U valine alanine aspartate glycine C valine alanine glutamate glycine A valine alanine glutamate glycine G U C A G 51. Using the codon table above, which DNA sequence was used as a template to produce the polypeptide sequence glycine - isoleucine - phenylalanine? (A) T (B) (C) (D) CCC TAG AAC CCG TAA AAG GGA TAC AAT GGC TAT AAA Answer Key: Biology 3201 August 2009 Page 10 of 21 52. Which process is occurring in the diagram below? (A) (B) T (C) (D) 53. Which type of mutation results in no change to the phenotype? (A) (B) T (C) (D) 54. elongation proofreading transcription translation mis-sense nonsense silent translocation What is the best explanation for the change shown in the diagram below? (A) (B) (C) T (D) A mutation was caused by the cold temperature. Cold temperature causes crossing over. Sorting and recombination of genes can be affected by cold temperatures. The environment can modify gene expression. Page 11 of 21 Answer Key: Biology 3201 August 2009 55. Which represents the situation below? Mutation 1 Mutation 2 Normal DNA Strand Normal Chromosome A B C AGT CGT AAG Abnormal DNA Strand Abnormal Chromosome C B A AGT TCG AAG 56. More Severe Amount of Genes Affected (A) Mutation 1 lower (B) Mutation 1 higher (C) Mutation 2 lower T (D) Mutation 2 higher Which is an example of monosomy? (A) (B) (C) T (D) 57. Which genetic disorder occurs through autosomal dominant inheritance? (A) T (B) (C) (D) 58. Down syndrome Jacobs syndrome Klinefelter syndrome Turner syndrome albinism Huntington’s sickle cell anemia Tay-Sachs Which could be the genotype of individual 1 in the pedigree shown below? (A) (B) (C) T (D) Ee only EE only Ee or ee EE or Ee Answer Key: Biology 3201 August 2009 Page 12 of 21 59. The pedigree below traces the inheritance of a metabolic disorder. Affected individuals are indicated by the darkened circles (female) and squares (male). What is the pattern of inheritance for this disorder? (A) (B) T (C) (D) 60. What is the function of a restriction enzyme? (A) T (B) (C) (D) 61. one sample of DNA, PCR amplification one sample of DNA, recombinant DNA two samples of DNA, PCR amplification two samples of DNA, recombinant DNA How can the technique shown in the diagram below be used to analyze a sample of DNA? DNA Samples (A) (B) T (C) (D) 63. carry DNA to a new cell cut DNA into many fragments link together fragments of DNA make numerous copies of a DNA segment Along with restriction enzymes and gel electrophoresis, what is the minimum requirement necessary to perform a DNA fingerprint? T (A) (B) (C) (D) 62. dominant allele incomplete dominance recessive allele sex-linkage produces genetically engineered DNA molecules removes the larger DNA fragments from the samples separates DNA fragments on the basis of size synthesizes large fragments of DNA Which describes a transgenic organism? T (A) (B) (C) (D) contains a gene from another species contains translocated genes produced by a polymerase chain reaction produced by cloning a mutant cell Page 13 of 21 Answer Key: Biology 3201 August 2009 64. Which characteristic would genetic engineers increase when trying to create a modified plant species? (A) T (B) (C) (D) 65. What is the meaning of the term “evolution”? (A) T (B) (C) (D) 66. (B) (C) T (D) Acquired characteristics are important for slow and gradual change in a population. Alleles located on chromosomes provide the means for variation in a population. Mutations are often harmful to a species. Organisms produce more offspring than can survive creating competition for resources. Which explains that, over evolutionary time, many cave-dwelling animals have lost their eyes and whales have lost their hind limbs? (A) T (B) (C) (D) 70. analagous structures cloning comparative anatomy industrial melanism Which statement is most directly associated with the research of Darwin? (A) 69. Human manipulation to obtain desired characteristics. Individuals must increase or decrease the use of some portion of their anatomy. One must observe more than one generation of the population. There must be the appearance of new species in the presence of existing species. Which is an example of modern day natural selection? (A) (B) (C) T (D) 68. For every new species, an old one vanishes. Gradual changes in a species can occur through time. Immediate changes arise because of mutations. Species remain stable over a long period of time. What must be done to observe the effects of natural selection on a population? (A) (B) T (C) (D) 67. fertilizer requirement resistance to pests susceptibility to herbicides water requirement artificial selection Having these structures created disadvantages for the organisms. theory of use and disuse These organisms experienced harmful mutations. Why do the embryos of animals like dogs, pigs and humans resemble one another in the early stages of development? T (A) (B) (C) (D) common ancestry same blood components similar habitat requirements similar number of chromosomes Answer Key: Biology 3201 August 2009 Page 14 of 21 71. Which describes the type of evolution of the two species of iguanas presented in the table below? Species A (A) (B) T (C) (D) 72. is rarely found more than 10 m from shore is found many meters inland from shore eats algae eats cactus and other land plants coevolution convergence divergence gene flow biochemical similarity embryonic similarity genetic variability homologous organs 30% 42% 70% 91% Which is a pre-zygotic barrier? (A) T (B) (C) (D) 75. spends most of its time on land In a population, 9% of individuals are homozygous dominant for tongue rolling. What percentage of individuals are heterozygous for tongue rolling? (A) T (B) (C) (D) 74. spends most of its time in the ocean What is illustrated by the fact that some hormones in humans are similar to those in pigs? T (A) (B) (C) (D) 73. Species B adaptive radiation behavioural isolation hybrid breakdown hybrid inviability The diagram below represents evolutionary pathways for two organisms. Which species was the most successful in the environment over time? (A) T (B) (C) (D) E F X Y Page 15 of 21 Answer Key: Biology 3201 August 2009 PART II Total Value: 25% Instructions: Complete all items in this section. Your responses should be clearly presented in a well-organized manner. Value 2% 76.(a) Describe one advantage and one disadvantage of a reflex arc response as compared to a normal response from the brain. Advantage: - quick - removal from danger - automatic Disadvantage: - may react inappropriately for the situation - over-reaction [1% awarded for one advantage, 1% awarded for one disadvantage] 3% (b) A researcher surgically removes the Islets cells from a rat’s pancreas to observe the effects. i) Describe two symptoms the rat should start exhibiting after the surgery. - thirsty - tiredness - frequent urination - inability to store sugar - loss/deterioration of vision [2% awarded for any two symptoms] ii) Explain one way the researcher could treat these symptoms. - give insulin - surgery - diet and exercise [1% for any of these possible solutions] Answer Key: Biology 3201 August 2009 Page 16 of 21 Value 3% 77.(a) Graph 1 below shows the hormone levels present in a female over 28 days. i) Explain two ways to cause the changes in hormone levels observed below in Graph 2. - pregnancy - oral contraceptive - depo-provera [½% awarded for each of 2 possible causes; ½% awarded for explanation of each cause given.] ii) Compare the roles of follicle stimulating hormone (FSH) in men and women. - In females, FSH cause follicles to mature an ovum. - In males, FSH stimulates sperm production. [½% each for the male and the female] Page 17 of 21 Answer Key: Biology 3201 August 2009 Value 4% 77.(b) A female patient is diagnosed with cancer and has to undergo both chemotherapy and radiation. i) Explain the effects of chemotherapy on the cellular processes of mitosis and meiosis. - In mitosis, chemotherapy will prevent cell division which is why it will stop the growth of cancerous cells. - In meiosis, chemotherapy will also prevent cell division. [1% awarded for discussing the effects on mitosis, 1% awarded for discussing the effects on meiosis] ii) Explain the effects of radiation on the cellular processes of mitosis and meiosis. - In mitosis, radiation will only affect the area being irradiated. It may cause mutations in that area. - In meiosis, radiation may cause sterility if the area of irradiation is in close proximity to the genitals. Can cause mutations in germ cells which can cause problems with offspring. [1% awarded for discussing the effects on mitosis, 1% awarded for discussing the effects on meiosis] 3% 78.(a) In humans, hemophilia is a sex-linked trait where normal clotting (H) is dominant and hemophilia (h) is recessive. Tongue rolling (T) is dominant to non-rolling (t). A non-hemophiliac male and a hemophiliac female produce a child. Both the male and the female are heterozygous for tongue rolling. What is the probability of this child being a hemophiliac who is a tongue roller? XHYTt crossed with XhXhTt XHt YT Yt XhT XHT XH XhTT XH XhTt XhYTT XhYTt Xht XH XhTt XH Xhtt XhYTt XhYtt 3/8 of children will be hemophiliac tongue rollers. 37.5% chance. [½% awarded for identifying each parents’ genotype. 1% awarded for correctly carrying out the cross (Punnet Square or Product Rule). 1% awarded for finding the correct fraction or percentage of offspring who will be hemophiliac tongue rollers] Answer Key: Biology 3201 August 2009 Page 18 of 21 Value 3% 78.(b) In the production of sperm cells, a nondisjunction event occurred with the sex chromosomes during meiosis II. i) Using the diagram below, outline a possible distribution of the sex chromosomes in the four sperm produced. Many chromosomal distributions were possible. Some of the possibilities are: Sperm Cell 1 Sperm Cell 2 Sperm Cell 3 Sperm Cell 4 XX XY YY null XX null Y Y X X YY null X Y XY null [½% awarded for each sperm cell completed with one of the possible sex cell chromosome distributions] ii) If the two affected sperm from this event fertilize two separate eggs, what two syndromes would be apparent in the offspring? Trisomies could result in Klinefelter, Jacobs, or Triple X syndromes. Monosomies could result in Turners syndrome. *Common error was listing Downs as a possible result, however Down’s is due to trisomy of autosomal chromosome 21. [½% awarded for each of one correct trisomy condition and one correct monosomy condition] Page 19 of 21 Answer Key: Biology 3201 August 2009 Value 3% 78.(c) Research has been done on the potential of changing the structure and function of human genetic material which is leading to improvements in medicine and health care for humans. i) Explain one way this knowledge has improved medicine and health care for humans. - treatment of disease - improved drug treatments [1% awarded for one way knowledge has improved medicine] ii) Describe one reason why the application of this knowledge might affect an individual’s privacy? - Insurance coverage - Job hiring - Right to privacy - Ethical reasons [1% awarded for listing one effect on privacy, 1% awarded for a description of how the effect might be felt] Answer Key: Biology 3201 August 2009 Page 20 of 21 Value 2% 79.(a) Explain how the population of birds described below will change over time, and state a factor that might influence this change. In birds, the ability to crush and eat seeds is related to the size, shape, and thickness of the beak. Birds with larger, thicker beaks are better adapted to crush and open seeds that are larger. One species of bird found in the Galapagos Islands is the medium ground finch. It is easier for most of the medium ground finches to pick up and crack open smaller seeds than larger seeds. When food is scarce, some of the birds have been observed eating larger seeds. - Directional Selection toward larger beaks OR - Disruptional Selection leading to speciation Competition is the primary factor which will influence change. Whether smaller will be out-competed by larger birds with larger beaks of the same species, or whether species with smaller beaks will be out-competed by species with larger beaks. * Common error: a small bird will grow a larger beak within its lifetime. [1% awarded for how, 1% awarded for the factor influencing the change] 2% (b) Due to the advanced development of antibiotics, scientists predicted that tuberculosis would be eradicated from the human population. Explain how, despite this prediction, there is now an increase of antibiotic resistant strains of tuberculosis. - bacterial resistence - mutations - over-prescribing of antibiotics - not taking the full prescription [1% awarded for stating how the antibiotic strains may have come about, 1% awarded for an explanation of the process by which resistence might occur.] Page 21 of 21 Answer Key: Biology 3201 August 2009