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Transcript
TO:
endoplasmic
reticulum
nucleus
protein
on its way!
DNA
RNA
TO:
vesicle
TO:
TO:
vesicle
TO:
ribosomes
finished
protein
protein
Golgi
apparatus
Making Proteins
RNA - Review



RNA is single stranded.
Instead of T it has U. (A,U,G,C)
3 kinds of RNA:



mRNA (messenger RNA)
Ribosomal RNA
tRNA (transfer RNA)

Where does
transcription
take place?
Transcription





Proteins attach to the DNA and unzip it.
Other proteins transcribe a strand of
DNA and make a messenger RNA
(mRNA)
The mRNA is single stranded.
The mRNA uses U instead of T.
(A,U,G,C)
The DNA zips back together.
Where does this take place?




Where is the DNA?
The nucleus.
How does the mRNA get out of the
nucleus?
The pore.
Nucleus
Where does it go to next?
To the Ribosome!



The ribosome is made of protein and
ribosomal RNA (rRNA).
All cells need proteins, DNA, and
ribosomes.
Prokaryotes & Eukaryotes have
ribosomes.
Translation

Where does
translation
take place?
Endoplasmic Reticulum –
Modifies Proteins


The ribosome can be free or
attached to the ER.
The finished protein can either be
modified or not.
It slides on the mRNA and
makes a protein.
Translation

Transfer RNA (tRNA) is RNA with an
amino acid attached to it.
amino
acid
amino
acid
Anti-codon
Translation


A codon is a 3 letter code.
The tRNA’s anti-codon lines up with
the mRNA’s codon with help from
the ribosome.
anti codon
codon
mRNA
Protein Synthesis Videos





Transcription –
http://www.youtube.com/watch?v=
WsofH466lqk
http://www.youtube.com/watch?v=
SMtWvDbfHLo&feature=relmfu
Translation –
http://www.youtube.com/watch?v=
5bLEDd-PSTQ&feature=related
http://www.youtube.com/watch?v=
TfYf_rPWUdY&feature=relmfu
Lets Do Transcription.
DNA to mRNA
T A C C G C G A T A C T C
mRNA to Amino Acid Sequence
A U G G C G C U A U G A G
Lets Do
Translation.
Practice
Makes
Perfect