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Leader: Stephanie Course: Bio 212 Instructor: Howell & Sakaguchi Supplemental Instruction Date: Nov 11, 2013 Iowa State University Study tip: If you can’t understand something from the book, see if there is an animation on youtube. Chapter 19:Developmental Biology Review: Ch 13 Draw the Lac Operon. Include the LacI, Z, Y, and A. What do each transcribe? Where are the LacP and O? Where does the Lac repressor and allolactose attach? What kind of transcriptional regulation is the lac operon? Chapter 19: Developmental genetics List 4 ways cells respond to positional information. Give an example of apoptosis in plants. Name two main molecular mechanisms use to communicate positional information How does bicoid accumulate in the anterior region of the oocyte? (Figure 1.9 is helpful) What would you expect to be the phenotype of a larva in which the bicoid gene was expressed in both the anterior region and the posterior region of the oocyte? What are homeotic genes? The colinearity rule? Give an example of homeotic mutation What phenotype would you expect if the Antp gene was expresses where abd-A is supposed to be expressed? (See figure 19.13) 1060 Hixson-Lied Student Success Center 515-294-6624 [email protected] http://www.si.iastate.edu If you observed fruit flies with the following developmental abnormalities, would you guess that a mutation has occurred in a segmentation gene or a homeotic gene? A) three abdominal segments were missing B) one abdominal segment had legs What group of proteins play a key role in controlling the program of developmental changes? Morphogens are…. The homeotic genes in Drosophila a. Determine the structural and functional characteristics of different segments of the developing fly b. Encode motor proteins that transport morphogens throughout the embryo c. Are dispersed apparently randomly throughout the gene d. Are expressed in similar levels in all parts of the developing embryo e. Both a and c Which of the following genes do not play a role in the process whereby segments are formed in the fruit fly embryo? a. Homeotic genes b. Gap genes c. Pair rule genes d. Segment polarity genes e. All of the above play a role in segmentation Give examples of the following Totipotent Pluripotent Multipotent Unipotent