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1. When the __ for insulin is inserted into bacteria, they can be used to mass-produce insulin. a) chromosome b) gene
c) fragment d) base
2. Who discovered the structure of DNA and made a model of it? a) Mendel b) Hershey and Chase c) Watson and Crick
d) Wilkins and Franklin
3. Which of the following is NOT matched correctly? a) Chargaff – A=T & C=G b) Hershey & Chase - radioactive
labels in virus DNA c) Griffith – X-ray diffraction photos d) Avery – DNA destroying enzymes
4. The base units of both DNA and RNA are a) amino acids b) nucleotides c) A, T, C, G d) A, C, G
5. Which is NOT correct? a) C is for cytosine b) tRNA is for transport RNA c) mRNA is for messenger RNA d) rRNA
is for ribosomal RNA
6. The “Father of Genetics was a) James Watson b)Erwin Chargaff c) Francis Crick d) Gregor Mendel
7. What carries amino acids to the ribosome during translation? a) tRNA b) rRNA c) mRNA d) DNA
8. Individuals with 3 chromosome 21s have Down syndrome. Down syndrome is caused by a) point mutation b)
frameshift mutation c) translocation d) nondisjuction
9. A change in an organisms genetic material is a) translation b) replication c) mutation d) transcription
10. Codons are 3-letter segments on mRNA that code for a) amino acids b) nucleotides c) mutations d) sugars
11. Changes in chromosome number are usually due to a) deletion b) nondisjunction c) duplication d) translocation
12. What makes up a ribosome? a) tRNA b) rRNA c) mRNA d) DNA
13. The process that makes a copy of RNA from DNA is a) translation b) replication c) mutation d) transcription
14. Which DNA strand would match up with this DNA: ATGC? a) ATGC b) TACG c) UACG d) CGTA
15. The process in which a gene is moved from one organism to another a) translocation b) genetic engineering c)
frameshift mutation d) transcription
16. It is the order of DNA’s __ that determines an organism’s traits. a) bases b) phosphates c) sugars d) amino acids
17. In DNA, A always matches with __ and C always matches with __. a) G, T b) T, G c) G, A d) T, A
18. Which is NOT true of chromosome mutations? a) translocation – a piece is doubled b) deletion – a piece is lost c)
inversion – a piece reattaches upside down d) duplication – a piece has 2 copies
19. When a defective gene is replaced with a good copy of the gene a) forensics b) gel electrophoresis c) translocation d)
gene therapy
20. Which is NOT correct? a) DNA helicase separates DNA bases b) DNA polymerase both separates bases and adds
matching bases c) RNA polymerase is used in transcription d) DNA polymerase is used in replication
21. What stores the protein code in the nucleus? a) tRNA b) rRNA c) mRNA d) DNA
22. Which BEST describes DNA’s shape? a) straight line b) steps c) twisted ladder d) curved
23. Scientists insert a jellyfish’s gene for bioluminence into a monkey. Who is the source organism? a) scientist b)
jellyfish c) monkey d) bacteria
24. Mutations can be passed to offspring if they a) happen in body cells b) are point mutations c) due to transcription
error d) happen in gametes
25. An mRNA has the codons AAA – UUU – CGC, but an A is deleted during transcription. What problem might this
cause? a) a chromosome mutation b) less chromosomes in a gamete c) a frameshift mutation d) a translocation
26. Mistakes in chromosome structure are made during a) translation b) crossing-over or replication c) transcription d) a
27. The failure of chromosomes to separate properly during meiosis is a) crossing-over b) nondisjunction c) frameshift
mutation d) point mutation
28. Which is found in RNA but not DNA? a) Adenine b) Thymine c) Guanine d) Uracil
29. Which is NOT correctly matched? a) sickle cell anemia – poor circulation b) hemophilia – mutated transport protein
c) cystic fibrosis – mucus clogs organs d) Turner’s syndrome – only 1 X chromosome
30. Which RNA strand would match up with this DNA: AGCA? a) UCGU b) UGCU c) TCGT d) AGCA
31. What carries the protein code from the nucleus to the ribosome? a) tRNA b) rRNA c) mRNA d) DNA
32. The process that produces protein using RNA is a) translation b) replication c) mutation d) transcription
33. What enzymes are used to cut DNA segments in genetic engineering? a) restriction b) DNA polymerase c) DNA
helicase d) RNA polymerase
34. A change in a single base of DNA or RNA is a __ mutation. a) chromosome b) frameshift c) point d) meiotic
35. Scientists insert a jellyfish’s gene for bioluminence into a monkey. Who is the target organism? a) scientist b)
jellyfish c) monkey d) bacteria
36. The DNA of two different organisms that have been combined in genetic engineering is called a) target DNA b)
source DNA c) recombinant DNA d) mDNA
37. Which is NOT true? a) gel electrophoresis produces DNA fingerprints b) forensics is the scientific investigation of
crime c) DNA samples can be obtained from hair, bone, or blood d) even identical twins have very different DNA
38. The process that makes a copy of DNA from DNA is a) translation b) replication c) mutation d) transcription
39. Griffith made his contribution to genetics by a) showing that viruses have DNA b) showing that bacteria can transfer
genetic material c) tracing DNA with radioactive labels d) making X-ray diffraction photographs
40. Cloning is accomplished by removing the __ from a cell of the wanted animal and inserting it into a “stripped” egg.
a) mitochondrion b) centrioles c) nucleus d) ribosome
Discussion (10 points each): Write one or more paragraphs to answer each question (a paragraph has 1 topic sentence &
at least 3 supporting sentences). Make sure your answers show: 1) CORRECTNESS, 2) ORGANIZATION,
3) COMPLETENESS, and 4) UNDERSTANDING. Draw pictures if necessary.
41. Discuss 2 differences and 2 similarities between DNA and RNA.
42. Describe what happens in each type of chromosome mutation: deletion, duplication, inversion, and translocation.