Download Genetic Organization and Control

Genetic Organization and Control
32: 1. What organisms did Barbara McClintock study?
2. What did she discover about crossing over frequency between the
genes of corn? (Hint…closer genes and further apart genes)
3. What did she create using crossover frequencies?
4. What does Ds stand for? Ac?
5. Which locus can insert into the colored gene and disrupt it?
6. What color will corn be if the colored gene is disrupted?
7. What is the term used for the gene “jumping” from one spot on the
chromosome to another?
8. Why would this “jumping” be advantageous for organisms?
39: 1. What can be found within a “band” on one chromosome?
2. What is a genome?
3. What percent of the human genome is actually made of genes?
4. Describe the steps that Venter used to create a Library of the
human brain genes.
5. What is cDNA?
6. When was the final draft of the human genome project published,
and by whom?
7. Is this draft without error?
40: 1. Why was Wigler concerned with the RAS gene?
2. What organism did Wigler try to isolate RAS from?
3. What steps did he take to find the RAS gene in yeast?
4. When comparing the RAS gene in humans and yeast, what did
Wigler find about the amino acid sequences?
Stop here on number 40
41: 1. What is Mario Capecchi studying?
2. Why is the human genome project important for his studies?
3.
What is the name for this type of study?
4. Whose experiment is this an outbranching of?
5. Why do people choose to use mice in studying human proteins?’
6. How did he study protein expression in mice? (Hint…it has to do
with color) Give a general description here. Don’t go into too
much detail.
Go to http://www.pbs.org/wgbh/nova/genome/sequencer.html# and
practice sequencing a human gene.