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Operon Control of Gene Expression Operon Control of Gene Expression An operon contains a collection of genes which are switched on and off together, as a unit. Operon Control of Gene Expression Here is the Tryptophan operon OR trp operon Operon Control of Gene Expression These five proteins allow the bacteria to synthesize trp ... and therefore survive. Operon Control of Gene Expression The trp operon Operon Control of Gene Expression The regulatory gene codes for the repressor Operon Control of Gene Expression Tryptophan interacts with the repressor to change it’s conformation. It can now bind with the operator. Operon Control of Gene Expression In the presence of trp the repressor binds to the operator, and blocks RNA polymerase Operon Control of Gene Expression An operon is a system which controls how genes are switched on and off together, as a unit. It is not the proteins that are produced that define an operon, an operon is a mechanism of control. An operon always contains several structural genes, an operator, and a promoter. Operon Control of Gene Expression Lactose operon OR lac operon Operon Control of Gene Expression The lac operon here is inactive, because the repressor is connected to the operator. Operon Control of Gene Expression The lac operon here is active. A single transcript is produced, with multiple start and stop codons. Operon Control of Gene Expression