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8/25/2011 Life’s molecular diversity is based on the properties of carbon Characteristic chemical groups help determine the properties of organic compounds 1 8/25/2011 Cells make a huge number of large molecules from a small set of small molecules 1 2 3 Making polymers by a Dehydration reaction Breaking polymers by a Hydrolysis reaction 2 8/25/2011 Four major macromolecules Carbohydrates Lipids (Fats) Proteins Nucleic Acids Monosaccharides are the simplest carbohydrates Cells link two single sugars to form disaccharides 3 8/25/2011 Polysaccharides are long chains of sugar units Fats are lipids that are mostly energystorage molecules Phospholipids and steroids are important lipids with a variety of functions 4 8/25/2011 Cholesterol, a steroid 3 1 4 2 Anabolic steroids pose health risks Proteins are essential to the structures and functions of life • Structural proteins: are found in hair and the fibers that make up connective tissues such as tendons and ligaments. • Contractile proteins: Found in muscles • Defensive proteins: The antibodies of the immune system • Signal proteins: Such as hormones that coordinate body activity 5 8/25/2011 More proteins • Receptor proteins: may be built into cell membranes and transmit signals into cells. • Transport proteins: Like hemoglobin transport oxygen in the red blood cells. • Storage proteins: such as ovalbumin, the protein of egg white, which serves as a source of amino acids for developing embryos. General structure of an amino acid Peptide bond formation 6 8/25/2011 A protein’s specific shape determines its function A protein’s shape depends on four levels of structure 1 3 2 4 Linus Pauling contributed to our understanding of the chemistry of life 7 8/25/2011 Nucleic acids are information-rich polymers of nucleotides Sugar-phosphate backbone DNA double helix 8