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Genetic modification Quick Write Write a few sentences about: Qualities you like about yourself Qualities you dislike about yourself If you could change any of these.. Would you? And why? Gene technologies & Human applications Manipulating Genes Genetic engineering - is the direct manipulation of an organism's genome using biotechnology. (Indirect genetic modification through artificial selection has been practiced for centuries.) Lab grown meat Lab grown meat Shoulder partner discussion: First student should ask: “Would you eat lab grown meat? Why?” Second student answer the question, then ask the same question to the other student. Listen and respect the other student, you will be asked to share Manipulating Genes Recombinant DNA - molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) to bring together genetic material from multiple sources, creating sequences that would not otherwise be found in biological organisms. Genetic engineering Jellyfish have a gene for bioluminescence Genetic engineering Recombinant DNA - molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) to bring together genetic material from multiple sources, creating sequences that would not otherwise be found in biological organisms. ??? Glowing Pig Glowing Cats Glowing Mice Can genetic engineering help? Causes of global warming Deforestation Methane CO2 emissions Cows that don’t fart methane Agree/Disagree: Designer baby Agree/Disagree: Plants that eat CO2 Agree/Disagree: Genetically modified foods Agree/Disagree: Medical benefit Agree/Disagree: Medical benefit Agree/Disagree: Cloning Designer Babies?! Say Whaaaa? https://www.youtube.com/watch?v=2ixEDLa3Jlc https://www.youtube.com/watch?v=mAmHoCbhyaw http://www.sciencechannel.com/tvshows/brink/videos/brink-designer-babies/ Bellwork: 2/15/17 Give 2 examples of how biotechnology is being used to benefit people and animals. (Two possible answers include insulin production and agents that eliminate blood clots.) List two things that the genes of a DNA molecule control. (Genes control an animal’s appearance, health, growth, and reproduction.) Explain any differences between a control group and an experimental group. (A major difference is that the control group contains all the same components as the experimental group except for what is being tested.) Surprising Human Genome Humans have only a few genes Most human DNA is non-coding Many human genes are identical to some nonhuman species All humans are genetically close Diagnosing & Preventing Disease Microarray - is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome. Diagnosing & Preventing Disease Genetic Counseling - is the process, by which patients or relatives, at risk of an inherited disorder, are advised of: 1) the consequences and nature of the disorder, 2) the probability of developing or transmitting it 3) the options open to them in management and family planning. Treating Disease Gene Therapy - is the use of DNA as a pharmaceutical agent to treat disease. It derives its name from the idea that DNA can be used to supplement or alter genes within an individual's cells as a therapy to treat disease. Treating Disease Pharmacogenomics - is the technology that analyses how genetic makeup affects an individual's response to drugs. Identifying individuals DNA finger printing - is a technique employed by forensic scientists to assist in the identification of individuals by their respective DNA profiles. Manipulating Bodies & Development Cloning - the process of producing similar populations of genetically identical individuals. Cloning Cloning Cloning Cloning Cloning Cloning Cloning Manipulating Bodies & Development Stem Cells- are undifferentiated biological cells, that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. Ethical & Social Issues Safety of Genetically modified food sources Property Laws: Patients rights: Do you own your genes? Patents: Pay for gene therapy that can save your life Copy written species: Bacteria as fuel sources Human rights: Who can we marry? Who should have access to genetic information? Decisions that effect children Reflection At the bottom of your notes, silently answer: What questions do you have about gene technologies and human applications? Letter to your Senator You have opinions, express them! Letter to your Senator You will write a letter to your Senator about your opinions on gene technologies Write if you agree or disagree with each genetic application Use vocabulary terms discussed in class You are writing to a Senator, so be sure to use your best English and writing skills Letter to your Senator Letter 5 4 3 2 1 0 Issues Three ethical issues addressed. The controversy surrounding each issue is explained. Three ethical issues are addressed, but some (1-2) are not explained. Less than three ethical issues are addressed. None of the ethical issues are explained. Opinions Clear, personal opinions provided for three ethical issues. Opinions are explained. Some (1-2) of the opinions are unclear or not personal. No opinion given. None of the opinions are clear nor personal. Vocabulary Words Correct use of five vocabulary words. Words are used in appropriate context. Five vocabulary words used, but some (1-3) are not used correctly. Less than five vocabulary words used. Vocabulary words are frequently (4 or more) used incorrectly. Mechanics No distracting grammatical and/or mechanical errors. Some (1-3) distracting grammatical and/or mechanical errors. Frequent (4 or more) distracting grammatical and/or mechanical errors. Score 5-0 Comments Total Score /20 Letter to your Senator You may listen to music as you write You may NOT talk Complete your letter before the end of class