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Genetic modification
Quick Write
Write a few sentences about:
Qualities you like about yourself
Qualities you dislike about yourself
If you could change any of these.. Would
you? And why?
Gene technologies &
Human applications
Manipulating Genes
 Genetic engineering - is the direct manipulation of
an organism's genome using biotechnology.
 (Indirect genetic modification through artificial
selection has been practiced for centuries.)
Lab grown meat
Lab grown meat
 Shoulder partner discussion:
 First student should ask: “Would you eat lab grown meat? Why?”
 Second student answer the question, then ask the same question
to the other student.
 Listen and respect the other student, you will be asked to share
Manipulating Genes
 Recombinant DNA - molecules are DNA molecules
formed by laboratory methods of genetic
recombination (such as molecular cloning) to bring
together genetic material from multiple sources,
creating sequences that would not otherwise be
found in biological organisms.
Genetic engineering
Jellyfish have a gene for bioluminescence
Genetic engineering
 Recombinant DNA - molecules are DNA molecules
formed by laboratory methods of genetic
recombination (such as molecular cloning)
to bring together genetic material from multiple
sources, creating sequences that would not otherwise
be found in biological organisms.
???
Glowing Pig
Glowing Cats
Glowing Mice
Can genetic engineering help?
Causes of global warming
Deforestation
Methane
CO2 emissions
Cows that don’t fart methane
Agree/Disagree: Designer baby
Agree/Disagree: Plants that eat CO2
Agree/Disagree:
Genetically modified foods
Agree/Disagree: Medical benefit
Agree/Disagree: Medical benefit
Agree/Disagree: Cloning
Designer Babies?! Say Whaaaa?
 https://www.youtube.com/watch?v=2ixEDLa3Jlc
 https://www.youtube.com/watch?v=mAmHoCbhyaw
 http://www.sciencechannel.com/tvshows/brink/videos/brink-designer-babies/
Bellwork: 2/15/17
 Give 2 examples of how biotechnology is being used to benefit
people and animals.
 (Two possible answers include insulin production and agents that
eliminate blood clots.)
 List two things that the genes of a DNA molecule control.
 (Genes control an animal’s appearance, health, growth, and
reproduction.)
 Explain any differences between a control group and an
experimental group.
 (A major difference is that the control group contains all the same
components as the experimental group except for what is being
tested.)
Surprising Human Genome
 Humans have only a few genes
 Most human DNA is non-coding
 Many human genes are identical to some nonhuman species
 All humans are genetically close
Diagnosing & Preventing Disease
 Microarray - is a collection of microscopic DNA spots
attached to a solid surface.
Scientists use DNA
microarrays to measure
the expression levels of
large numbers of genes
simultaneously or to
genotype multiple
regions of a genome.
Diagnosing & Preventing Disease
 Genetic Counseling - is the process, by which patients
or relatives, at risk of an inherited disorder, are
advised of:
1) the consequences and nature of the disorder,
2) the probability of developing or transmitting it
3) the options open to them in management and
family planning.
Treating Disease
 Gene Therapy - is the use of DNA as a
pharmaceutical agent to treat disease.
 It derives its name from the idea that DNA can be
used to supplement or alter genes within an
individual's cells as a therapy to treat disease.
Treating Disease
 Pharmacogenomics - is the technology that analyses
how genetic makeup affects an individual's response
to drugs.
Identifying individuals
 DNA finger printing - is a technique employed by
forensic scientists to assist in the identification of
individuals by their respective DNA profiles.
Manipulating Bodies & Development
 Cloning - the process of producing similar
populations of genetically identical individuals.
Cloning
Cloning
Cloning
Cloning
Cloning
Cloning
Cloning
Manipulating Bodies & Development
 Stem Cells- are undifferentiated biological cells, that
can differentiate into specialized cells and can
divide (through mitosis) to produce more stem cells.
Ethical & Social Issues
 Safety of Genetically modified food sources
 Property Laws:
 Patients rights: Do you own your genes?
 Patents: Pay for gene therapy that can save your life
 Copy written species: Bacteria as fuel sources
 Human rights:
 Who can we marry?
 Who should have access to genetic information?
 Decisions that effect children
Reflection
 At the bottom of your notes, silently answer:
What questions do you have about gene technologies
and human applications?
Letter to your Senator
You have opinions, express them!
Letter to your Senator
 You will write a letter to your Senator about your opinions
on gene technologies
 Write if you agree or disagree with each genetic
application
 Use vocabulary terms discussed in class
 You are writing to a Senator, so be sure to use your
best English and writing skills
Letter to your Senator
Letter
5
4
3
2
1
0
Issues
Three ethical issues
addressed. The controversy
surrounding each issue is
explained.
Three ethical issues are
addressed, but some (1-2)
are not explained.
Less than three ethical issues
are addressed. None of the
ethical issues are explained.
Opinions
Clear, personal opinions
provided for three ethical
issues. Opinions are
explained.
Some (1-2) of the opinions
are unclear or not personal.
No opinion given. None of
the opinions are clear nor
personal.
Vocabulary
Words
Correct use of five
vocabulary words. Words
are used in appropriate
context.
Five vocabulary words used,
but some (1-3) are not used
correctly.
Less than five vocabulary
words used. Vocabulary
words are frequently (4 or
more) used incorrectly.
Mechanics
No distracting grammatical
and/or mechanical errors.
Some (1-3) distracting
grammatical and/or
mechanical errors.
Frequent (4 or more)
distracting grammatical
and/or mechanical errors.
Score
5-0
Comments
Total Score
/20
Letter to your Senator
You may listen to music as you write
You may NOT talk
Complete your letter before the end of class