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CAMPBELL BIOLOGY IN FOCUS
Urry • Cain • Wasserman • Minorsky • Jackson • Reece
13
The Molecular
Basis of Inheritance
Questions prepared by
Brad Stith, University of Colorado Denver
Louise Paquin, McDaniel College
Christopher Gregg, Louisiana State University
© 2014 Pearson Education, Inc.
Who conducted the X-ray diffraction studies that
were key to the discovery of the structure of DNA?
A. Griffith
B. Franklin
C. Meselson and Stahl
D. Chargaff
E. McClintock
© 2014 Pearson Education, Inc.
Who conducted the X-ray diffraction studies that
were key to the discovery of the structure of DNA?
A. Griffith
B. Franklin
C. Meselson and Stahl
D. Chargaff
E. McClintock
© 2014 Pearson Education, Inc.
How do the leading and the lagging strands differ?
A. The leading strand is synthesized in the same
direction as the movement of the replication fork,
and the lagging strand is synthesized in the opposite
direction.
B. The leading strand is synthesized at twice the rate of the
lagging strand.
C. The lagging strand is synthesized continuously, whereas
the leading strand is synthesized in short fragments that
are ultimately stitched together.
D. The leading strand is synthesized by adding nucleotides
to the 3' end of the growing strand, and the lagging strand
is synthesized by adding nucleotides to the 5' end.
© 2014 Pearson Education, Inc.
How do the leading and the lagging strands differ?
A. The leading strand is synthesized in the same
direction as the movement of the replication fork,
and the lagging strand is synthesized in the opposite
direction.
B. The leading strand is synthesized at twice the rate of the
lagging strand.
C. The lagging strand is synthesized continuously, whereas
the leading strand is synthesized in short fragments that
are ultimately stitched together.
D. The leading strand is synthesized by adding nucleotides
to the 3' end of the growing strand, and the lagging strand
is synthesized by adding nucleotides to the 5' end.
© 2014 Pearson Education, Inc.
What kind of evidence about the structure of DNA
came from each of the following branches of
science?
A. physics
B. chemistry
C. biology
© 2014 Pearson Education, Inc.
If the result of the Hershey and Chase experiment
had been that radioactive sulfur (35S) was found
inside the cells instead of radioactive phosphorous
(32P), what could have been concluded?
© 2014 Pearson Education, Inc.
Define and diagram “semiconservative” as it applies
to DNA replication.
© 2014 Pearson Education, Inc.
Telomeres, or the ends of linear chromosomes,
have special structure and function, even though
they are noncoding. Describe their structure and
function.
© 2014 Pearson Education, Inc.
What enzyme does a gamete-producing cell include
that compensates for replication-associated
shortening?
A. DNA polymerase II
B. ligase
C. telomerase
D. DNA nuclease
E. proofreading enzyme
© 2014 Pearson Education, Inc.
What enzyme does a gamete-producing cell include
that compensates for replication-associated
shortening?
A. DNA polymerase II
B. ligase
C. telomerase
D. DNA nuclease
E. proofreading enzyme
© 2014 Pearson Education, Inc.
Which of the following is true of heterochromatin
but not of euchromatin?
A. It is accessible to enzymes needed for gene
expression.
B. It becomes less tightly compacted after cell
division.
C. It includes DNA primarily found in expressed
genes.
D. It appears more pale when observed
microscopically.
E. It remains tightly coiled at the G1 phase.
© 2014 Pearson Education, Inc.
Which of the following is true of heterochromatin
but not of euchromatin?
A. It is accessible to enzymes needed for gene
expression.
B. It becomes less tightly compacted after cell
division.
C. It includes DNA primarily found in expressed
genes.
D. It appears more pale when observed
microscopically.
E. It remains tightly coiled at the G1 phase.
© 2014 Pearson Education, Inc.
Which of the following is an example of
“recombinant DNA”?
A. combining alternate alleles of a gene in a
single cell
B. manipulating a meiotic crossing-over event
C. cloning genes from homologous pairs of
chromosomes
D. introducing a human gene into a bacterial
plasmid
E. alternate alleles assorting independently
© 2014 Pearson Education, Inc.
Which of the following is an example of
“recombinant DNA”?
A. combining alternate alleles of a gene in a
single cell
B. manipulating a meiotic crossing-over event
C. cloning genes from homologous pairs of
chromosomes
D. introducing a human gene into a bacterial
plasmid
E. alternate alleles assorting independently
© 2014 Pearson Education, Inc.
This segment of DNA is cut at restriction sites 1 and 2,
which creates restriction fragments A, B, and C. Which
of the following electrophoretic gels represents the
separation of these fragments?
A.
B.
C.
D.
© 2014 Pearson Education, Inc.
This segment of DNA is cut at restriction sites 1 and 2,
which creates restriction fragments A, B, and C. Which
of the following electrophoretic gels represents the
separation of these fragments?
A.
B.
C.
D.
© 2014 Pearson Education, Inc.