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Transcript
Discuss with the following questions with the person (or people) next to you: 1.What are the potential benefits to knowing more about your genetic predisposition to disease? 2.What are the possible negatives to knowing? Because learning about our own DNA is rapidly becoming inexpensive and accessible Insights about our health, behavior, family history and other traits Highly personal information with personal, social and familial impact Genetic testing available directly to consumers “Under $1000 dollars in this decade” “Widely available in the next 5-10 years” “Transforming health care for the next generation” Sources: New York Times A true story highlights the promise of personalized medicine http://www.nature.com/news/2011/110615/full/news.2011.368.html Personal Choices Based on Genetic Information Angelina Jolie reveals she chose to undergo a double mastectomy Jolie had a genetic test and found she carried a genetic mutation – doctors estimated an 87% chance she would get breast cancer Non-Invasive Prenatal Testing »Fetus and mother share a blood supply »Fetal cells release DNA that enters the maternal blood stream »Maternal blood now contains a mixture of maternal cell-free DNA and fetal cell-free DNA http://www.monashultrasound.com.au/images/NIPT_clip_image003.jpg “DNA tests locate genetic branches of African American’s family trees” http://www.post-gazette.com/stories/life/lifestyle/dna-tests-locate-genetic-branches-on-african-americans-family-trees-427734/ Photo credit: Steve Mellon Technological Advances ENIAC iPad 1946 2012 Genome Sequencing Technology Applied Biosystems 3730 DNA Analyzers Oxford Nanopore MinION 2002 2012 Direct-to-consumer analysis for sale on the internet Health-related Risks 1)How far ahead is the technology of its clinical usefulness? 2)How much might this information impact you and your family? 3)Will fair weight be given to environmental & social factors? 4)How much should we be concerned about discrimination at work and by insurance companies? 5)How can we ensure access for all?
