Download What are the potential benefits to knowing more - B

Discuss with the following
questions with the person (or
people) next to you:
1.What are the potential benefits to knowing
more about your genetic predisposition to
disease?
2.What are the possible negatives to
knowing?
Because learning about our own DNA is rapidly
becoming inexpensive and accessible
Insights about our health, behavior, family
history and other traits
Highly personal information with personal,
social and familial impact
Genetic testing available directly to consumers
“Under $1000 dollars in this decade”
“Widely available in the next 5-10 years”
“Transforming health care for the next generation”
Sources: New York Times
A true story
highlights the
promise
of personalized
medicine
http://www.nature.com/news/2011/110615/full/news.2011.368.html
Personal Choices Based on Genetic Information
Angelina Jolie reveals she
chose to undergo a double
mastectomy
Jolie had a genetic test
and found she carried a
genetic mutation – doctors
estimated an 87% chance
she would get breast
cancer
Non-Invasive Prenatal Testing
»Fetus and mother share
a blood supply
»Fetal cells release DNA
that enters the maternal
blood stream
»Maternal blood now
contains a mixture of
maternal cell-free DNA
and fetal cell-free DNA
http://www.monashultrasound.com.au/images/NIPT_clip_image003.jpg
“DNA tests locate genetic branches
of African American’s family trees”
http://www.post-gazette.com/stories/life/lifestyle/dna-tests-locate-genetic-branches-on-african-americans-family-trees-427734/
Photo credit: Steve Mellon
Technological Advances
ENIAC
iPad
1946
2012
Genome Sequencing Technology
Applied Biosystems 3730
DNA Analyzers
Oxford Nanopore MinION
2002
2012
Direct-to-consumer analysis for sale on the internet
Health-related Risks
1)How far ahead is the technology of its clinical
usefulness?
2)How much might this information impact you
and your family?
3)Will fair weight be given to environmental &
social factors?
4)How much should we be concerned about
discrimination at work and by insurance
companies?
5)How can we ensure access for all?