Download C483 Study Guide for Exam 2 Fall 2015 Basic Information Exam 3

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Transcript
C483 Study Guide for Exam 2
Fall 2015
Basic Information
 Exam 3: Thursday, December 3, 7:15-9:15PM in Fine Arts o15
 Arrive early for assigned seats
 Bring your student ID. Failure to do so will result in getting your exam back later.
 You may use a NON-PROGRAMMABLE calculator.
 All papers, books, phones, and electronic devices must be in a sealed bag under your seat.
The exam will cover chapters 13-15 and 17, which includes
 Glycolysis, gluconeogenesis, glycogen metabolism, pentose phosphate pathway
 Pyruvate dehydrogenase complex, citric acid cycle
 Electron transport chain, protonmotive force, oxidative phosphorylation
 Fatty acid degradation and synthesis, cholesterol synthesis and processing
Major topics
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Stages/major purpose/net reaction for pathways
Intermediates of glycolysis, gluconeogenesis, citric acid cycle, glycogen metabolism,
fatty acid metabolism
o Structure and name
o Recognize enzyme names
o Thermodynamics of each step, qualitative and quantitative
o Major regulation steps; reciprocal regulation strategies
o Points of interconnection between pathways
o Amount of ATP/reduced cofactor produced in each step
o Cofactors needed for transformation
o Arrow mechanisms if mechanism is given in notes
Pentose phosphate pathway: know stages, purposes, 4 modes, which type of enzyme
needed for a given transformation, transketalase mechanism
Electron transport chain/oxidative phosphorylation
o Order of main complexes and mobile carriers (not details of complexes)
o Number of protons pumped
o Qualitative/quantitative redox reactions
o P:O ratio
o Basic mechanism of binding-change ATP production
Practice:


Homework
Big picture type questions
o Starting with __________, how many ATP could be obtained upon catabolism to
CO2?
o How would a rise/fall in [intermediate] affect the rate of _______ and
__________ pathways?